Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension


Konukoglu D. , Serin O., Turhan M. S.

ARCHIVES OF MEDICAL RESEARCH, cilt.37, ss.602-606, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 37 Konu: 5
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.arcmed.2005.12.002
  • Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
  • Sayfa Sayıları: ss.602-606

Özet

Background. Recent evidence suggested that leptin-induced oxidative stress in human endothelial cells in vivo and increased oxidative stress in human essential hypertension may further contribute to both the development of atherosclerosis and other cardiovascular diseases. We investigated the association of plasma leptin levels with plasma lipid peroxidation and nitric oxide metabolites (NOx) in obese hypertensive atherosclerosis model.