Human papillomavirus in a patient with severe gingival overgrowth associated with cyclosporine therapy. A case report

Saglam F., Onan U., Soydinc M., Yilmaz O., Kirac K., Sever M.

JOURNAL OF PERIODONTOLOGY, cilt.67, sa.5, ss.528-531, 1996 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 5
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1902/jop.1996.67.5.528
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.528-531
  • İstanbul Üniversitesi Adresli: Hayır

Özet

CYCLOSPORIN A IS AN ENDECAPEPTIDE that has been used clinically since 1978 as an immunosuppressant agent. Although cyclosporine appears to be uniformly beneficial in the treatment of a wide variety of disorders, its use may result in a number of side effects. One of the most important adverse effects is gingival overgrowth. This report relates a case of severe gingival overgrowth in a 31-year-old female who had received cyclosporine therapy in conjunction with a kidney transplant. Because of the severe gingival overgrowth, we analyzed a biopsy, which was positive for human papillomavirus. The case was treated and followed for 18 months.