Phytochemical Investigation of Leontice leontopetalum L. subsp ewersmannii with Antioxidant and Anticholinesterase Activities
RECORDS OF NATURAL PRODUCTS, vol.5, no.4, pp.309-313, 2011 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 5 Issue: 4
- Publication Date: 2011
- Journal Name: RECORDS OF NATURAL PRODUCTS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.309-313
- Keywords: Leontice leontopetalum L. subsp ewersmannii, Berberidaceae, lupanine, anticholinesterase, ALKALOIDS
- Istanbul University Affiliated: Yes
Abstract
Two known quinolizidine alkaloids, lupanine and leontiformidine, were isolated from the tubers of L. leontopetalum subsp. ewersmannii. Lupanine having the highest inhibition of lipid peroxidation at 100 mu g/mL among the tested samples indicated almost the same ABTS cation radical scavenging activity with BHT, alpha-tocopherol and (+)-catechin at the same concentration. Lupanine and the alkaloidal extract showed almost the same butyrylcholinesterase inhibitory activity with galantamine at 200 mu g/mL.