Phytochemical Investigation of Leontice leontopetalum L. subsp ewersmannii with Antioxidant and Anticholinesterase Activities
RECORDS OF NATURAL PRODUCTS, cilt.5, sa.4, ss.309-313, 2011 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 5 Sayı: 4
- Basım Tarihi: 2011
- Dergi Adı: RECORDS OF NATURAL PRODUCTS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.309-313
- Anahtar Kelimeler: Leontice leontopetalum L. subsp ewersmannii, Berberidaceae, lupanine, anticholinesterase, ALKALOIDS
- İstanbul Üniversitesi Adresli: Evet
Özet
Two known quinolizidine alkaloids, lupanine and leontiformidine, were isolated from the tubers of L. leontopetalum subsp. ewersmannii. Lupanine having the highest inhibition of lipid peroxidation at 100 mu g/mL among the tested samples indicated almost the same ABTS cation radical scavenging activity with BHT, alpha-tocopherol and (+)-catechin at the same concentration. Lupanine and the alkaloidal extract showed almost the same butyrylcholinesterase inhibitory activity with galantamine at 200 mu g/mL.