Inhibition of Aspergillus fumigatus and Its Biofilm by Pseudomonas aeruginosa Is Dependent on the Source, Phenotype and Growth Conditions of the Bacterium

---

Copy For Citation

Ferreira J. A. G., Penner J. C., Moss R. B., Haagensen J. A. J., Clemons K. V., Spormann A. M., ...More

PLOS ONE, vol.10, no.8, 2015 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 10 Issue: 8
• Publication Date: 2015
• Doi Number: 10.1371/journal.pone.0134692
• Journal Name: PLOS ONE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Istanbul University Affiliated: Yes

Abstract

Aspergillus fumigatus (Af) and Pseudomonas aeruginosa (Pa) are leading fungal and bacterial pathogens, respectively, in many clinical situations. Relevant to this, their interface and co-existence has been studied. In some experiments in vitro, Pa products have been defined that are inhibitory to Af. In some clinical situations, both can be biofilm producers, and biofilm could alter their physiology and affect their interaction. That may be most relevant to airways in cystic fibrosis (CF), where both are often prominent residents.