Investigation of DNA damage in lymphocytes exposed to benzathine penicillin G
PEDIATRICS INTERNATIONAL, vol.46, no.4, pp.415-418, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 46 Issue: 4
- Publication Date: 2004
- Doi Number: 10.1111/j.1442-200x.2004.01930.x
- Journal Name: PEDIATRICS INTERNATIONAL
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.415-418
- Istanbul University Affiliated: No
Abstract
Background: Benzathine penicillin G (BPG) is a widely used antibiotic for treatment or prophylaxis of certain infectious diseases. Previous in vivo studies using sister chromatid exchange (SCE) frequency and comet assay, had showed that long-term administration of benzathine penicillin G may cause some degree of DNA damage in children with rheumatic fever.