Akademik Veri Yönetim Sistemi
Istanbul Tip Fakultesi Mecmuasi, cilt.59, sa.1, ss.45-48, 1996 (Scopus)
In this prospective study, 24 patients to whom renal biopsy was performed with a probable diagnosis of primary glomerular disease in Nephrology Department of Medical School of Istanbul, between 10.12.1991 and 14.7.1992, are reported. Eight of the 24 (33%) patients were found to have IgA nephropathy. Four of them were male and 4 female with a mean age of 24.5 5.9 (range 15 to 32) years. Skin punch biopsy was applied to 7 patients and no significant IBA deposition was detected in dermal capillaries. Two of the 8 (25%) patients had high serum IgA levels. The higher incidence of IgA nephropathy in some countries is attributed to routinely done urinary screening tests and frequently performed kidney biopsies in asymptomatic urinary abnormalities. Our relatively high rate of IgA nephropathy can be explained on the basis of high index of suspicion and broad indication for kidney biopsy in asymptomatic urinary abnormalities. In conclusion, IgA nephropathy is not an infrequent disease. In the diagnosis of this disease, we suggest that measurement of serum IgA levels is helpful although skin punch biopsy was found to be unuseful.