Assessment of IL-31 levels and disease severity in children with atopic dermatitis.

Ozceker D., Bulut M., Ozbay A. C., Dilek F., Koser M., Tamay Z. Ü., ...Daha Fazla

Allergologia et immunopathologia, cilt.46, sa.4, ss.322-325, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.aller.2017.10.005
  • Dergi Adı: Allergologia et immunopathologia
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.322-325
  • Anahtar Kelimeler: Atopic dermatitis, Pruritus, Children, Interleukin 31, T-CELLS, INTERLEUKIN-31, EXPRESSION, CORRELATE, PRURITUS, ITCH
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction and objectives: Atopic dermatitis is a chronic, relapsing, highly pruritic, inflam- matory skin disease characterized by typical localization with increasing prevalence of 10-20% in children. Pruritus is one of the major diagnostic criteria of atopic dermatitis and also the main complaint altering quality-of-life of affected patients, inducing and aggravating inflammation. Although pruritus is the absolute symptom of AD, the etiology has not been fully explained yet and current antihistamine therapies are ineffective.