Assessment of IL-31 levels and disease severity in children with atopic dermatitis.
Allergologia et immunopathologia, cilt.46, sa.4, ss.322-325, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 46 Sayı: 4
- Basım Tarihi: 2018
- Doi Numarası: 10.1016/j.aller.2017.10.005
- Dergi Adı: Allergologia et immunopathologia
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.322-325
- Anahtar Kelimeler: Atopic dermatitis, Pruritus, Children, Interleukin 31, T-CELLS, INTERLEUKIN-31, EXPRESSION, CORRELATE, PRURITUS, ITCH
- İstanbul Üniversitesi Adresli: Evet
Özet
Introduction and objectives: Atopic dermatitis is a chronic, relapsing, highly pruritic, inflam- matory skin disease characterized by typical localization with increasing prevalence of 10-20% in children. Pruritus is one of the major diagnostic criteria of atopic dermatitis and also the main complaint altering quality-of-life of affected patients, inducing and aggravating inflammation. Although pruritus is the absolute symptom of AD, the etiology has not been fully explained yet and current antihistamine therapies are ineffective.