Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand?

El-Khouly, Fatma; van Zanten, Sophie; Santa-Maria Lopez, Vicente; Hendrikse, N.; Kaspers, Gertjan; Loizos, G.; Sumerauer, David; Nysom, Karsten; Pruunsild, Kaie; Pentikainen, Virve; Thorarinsdottir, Halldora; Rutkauskiene, Giedre; Calvagna, Victor; Drogosiewicz, Monika; Dragomir, Monica; Deak, Ladislav; Kitanovski, Lidija; von Bueren, Andre; KEBUDİ, Rejin; Slavc, Irene; Jacobs, Sandra; Jadrijevic-Cvrlje, Filip; Entz-Werle, Natacha; Grill, Jacques; Kattamis, Antonis; Hauser, Peter; Pears, Jane; Biassoni, Veronica; Massimino, Maura; Lopez Aguilar, Enrique; Torsvik, Ingrid; Gil-da-Costa, Maria; Kumirova, Ella; Cruz-Martinez, Ofelia; Holm, Stefan; Bailey, Simon; Hayden, Tim; Thomale, Ulrich; Janssens, Geert; Kramm, Christof; van Vuurden, Dannis

doi:10.1007/s11060-019-03287-9

Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand?

El-Khouly F. E., van Zanten S. E. M. V., Santa-Maria Lopez V., Hendrikse N. H., Kaspers G. J. L., Loizos G., ...More

JOURNAL OF NEURO-ONCOLOGY, vol.145, no.1, pp.177-184, 2019 (SCI-Expanded)

Publication Type: Article / Article
Volume: 145 Issue: 1
Publication Date: 2019
Doi Number: 10.1007/s11060-019-03287-9
Journal Name: JOURNAL OF NEURO-ONCOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.177-184
Keywords: Diffuse intrinsic pontine glioma (DIPG), Diffuse midline glioma H3-K27 mutant (DMG K3-27M), Chemotherapy, Radiotherapy, BRAIN-STEM GLIOMA, CHILDREN, COHORT, PROGNOSIS, TUMORS
Open Archive Collection: AVESIS Open Access Collection
Istanbul University Affiliated: Yes

Abstract

Introduction Diffuse intrinsic pontine glioma (DIPG) is a rare clinically, neuro-radiologically, and molecularly defined malignancy of the brainstem with a median overall survival of approximately 11 months. Our aim is to evaluate the current tendency for its treatment in Europe in order to develop (inter)national consensus guidelines.