A young female patient with an androgen-secreting tumor: A rare malignant disease


Bozbora A., Erbil Y., Ozbey N., Kapran Y., Ozarmagan S., Berber E., ...Daha Fazla

TUMORI, cilt.86, sa.6, ss.487-488, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 86 Sayı: 6
  • Basım Tarihi: 2000
  • Dergi Adı: TUMORI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.487-488
  • İstanbul Üniversitesi Adresli: Hayır

Özet

A 23-year-old female patient presented with hirsutism and fatigue nine months after delivery, Endocrine assessment showed high testesterone, DHEA-S and androstenedione levels. Abdominal computed tomography and ultrasonography revealed the presence of a large tumor in the right renal region. Right adrenalectomy was performed resulting in a diagnosis of a functional adrenal tumor. Pathological examination showed a steroidogenically active tumor. Adjuvant chemotheraphy was administered postoperatively, At three months following surgery all endocrinological tests normalized, but river metastases were detected by abdominal CT, Eight months after the operation the patient died of hepatic and renal failure, Androgen-secreting adrenal tumors are seen Very rarely yet the prognosis is poor due to their agressive nature.