Protective effect of dexpanthenol against nephrotoxic effect of amikacin: An experimental study

Dogan E. E., Erkoc R., Ekinci I., Hamdard J., Doner B., Cikrikcioglu M. A., ...Daha Fazla

BIOMEDICINE & PHARMACOTHERAPY, cilt.89, ss.1409-1414, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 89
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.biopha.2017.03.019
  • Dergi Adı: BIOMEDICINE & PHARMACOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1409-1414
  • Anahtar Kelimeler: Amikacin, Dexpanthenol, Nephrotoxicity, Oxidative stress, PANTOTHENIC-ACID, GLUTATHIONE, EXTRACT, INJURY, DAMAGE
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Background: Amikacin has the largest spectrum among aminoglycosides, its nephrotoxic effect limits its utilization. Our purpose in this study is to review the protective effect of dexpanthenol against the nephrotoxic effect of amikacin, accompanied with histopathological and biochemical parameters.