Angiotensin-converting enzyme I/D gene polymorphisms and effects of left ventricular hypertrophy in Turkish myocardial infarction patients
ACTA CARDIOLOGICA, cilt.59, sa.5, ss.493-497, 2004 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 59 Sayı: 5
- Basım Tarihi: 2004
- Doi Numarası: 10.2143/ac.59.5.2005221
- Dergi Adı: ACTA CARDIOLOGICA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.493-497
- Anahtar Kelimeler: angiotensin-converting enzyme polymorphism, left ventricular hypertrophy, myocardial infarction, CORONARY-ARTERY-DISEASE, IDIOPATHIC DILATED CARDIOMYOPATHY, INSERTION DELETION POLYMORPHISM, DEPENDENT DIABETES-MELLITUS, ISCHEMIC-HEART-DISEASE, INCREASED RISK, ASSOCIATION, LOCUS, HYPERTENSION, POPULATIONS
- İstanbul Üniversitesi Adresli: Evet
Özet
Objective - Since the initial report of the association of the deletion/insertion (D/I) polymorphism in the gene for angiotensin-converting enzyme (ACE) with myocardial infarction (MI), there has been considerable controversy. Some have found the D allele to be associated with MI, coronary heart disease (CHD) or other cardiac pathologies, while others have not. In view of the clinical importance of the ACE as a major marker of cardiovascular diseases, we investigated the I/D polymorphism of the ACE gene in Turkish patients with acute myocardial infarction in comparison with control subjects.