Angiotensin-converting enzyme I/D gene polymorphisms and effects of left ventricular hypertrophy in Turkish myocardial infarction patients


KARAALI Z., Agachan B. , YILMAZ H. , ISBIR T.

ACTA CARDIOLOGICA, vol.59, pp.493-497, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 5
  • Publication Date: 2004
  • Doi Number: 10.2143/ac.59.5.2005221
  • Title of Journal : ACTA CARDIOLOGICA
  • Page Numbers: pp.493-497

Abstract

Objective - Since the initial report of the association of the deletion/insertion (D/I) polymorphism in the gene for angiotensin-converting enzyme (ACE) with myocardial infarction (MI), there has been considerable controversy. Some have found the D allele to be associated with MI, coronary heart disease (CHD) or other cardiac pathologies, while others have not. In view of the clinical importance of the ACE as a major marker of cardiovascular diseases, we investigated the I/D polymorphism of the ACE gene in Turkish patients with acute myocardial infarction in comparison with control subjects.