Choroidal involvement in systemic vasculitis: a systematic review

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Ozdal P. C., Tugal-Tutkun I.

JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION, cilt.12, sa.1, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 12 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1186/s12348-022-00292-4
  • Dergi Adı: JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, Directory of Open Access Journals
  • Anahtar Kelimeler: Systemic vasculitis, Choroidal involvement, Ischemia, Inflammation, Multimodal imaging, OPTICAL COHERENCE TOMOGRAPHY, CENTRAL SEROUS CHORIORETINOPATHY, INDOCYANINE GREEN ANGIOGRAPHY, RETINAL ARTERY-OCCLUSION, OCULAR MANIFESTATIONS, LUPUS-ERYTHEMATOSUS, FLUORESCEIN ANGIOGRAPHY, RHEUMATOID-ARTHRITIS, WEGENERS-GRANULOMATOSIS, CLINICAL-FEATURES
  • İstanbul Üniversitesi Adresli: Evet

Özet

Systemic vasculitides are a large group of heterogeneous diseases characterized by inflammatory destruction of blood vessels targeting diverse organs and tissues including the eye. As the most vascularized layer of the eye, the choroid is expected to be affected in multiple systemic rheumatologic diseases with vascular involvement. While there are plenty of studies investigating retinal vascular involvement, choroidal vascular involvement in systemic vasculitides has not been investigated in isolation. However, choroidal manifestations including thickness changes, choroidal vasculitis and ischemia may be the earliest diagnostic features of systemic vasculitic diseases. Thus, multimodal imaging of the choroid may help early detection of choroidal involvement which may also have prognostic implications in these life-threatening diseases. This article aimed to review involvement of the choroid in systemic vasculitic diseases.