Synthesis and antitubercular activity of 4-(3-coumarinyl)-3-cyclohexyl-4-thiazolin-2-one benzylidenehydrazones


Karali N. L. , Kocabalkanli A., Gursoy A., Ates O.

FARMACO, cilt.57, ss.589-593, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

In this study, a new series of 4-(3-coumarinyl)-3-cyclohexyl-4-thiazoline-2-one benzylidene hydrazones (3a-p) were synthesized. Structures of the title compounds were determined by analytical and spectral methods. 3a-p were evaluated for antituberculosis activity against Mycobacterium tuberculosis H37Rv. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.