Synthesis and antitubercular activity of 4-(3-coumarinyl)-3-cyclohexyl-4-thiazolin-2-one benzylidenehydrazones

Karali N. L., Kocabalkanli A., Gursoy A., Ates O.

FARMACO, cilt.57, sa.7, ss.589-593, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 7
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1016/s0014-827x(02)01254-5
  • Dergi Adı: FARMACO
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.589-593
  • Anahtar Kelimeler: coumarins, thiazolines, benzylidene hydrazones, antitubercular activity, DERIVATIVES
  • İstanbul Üniversitesi Adresli: Evet

Özet

In this study, a new series of 4-(3-coumarinyl)-3-cyclohexyl-4-thiazoline-2-one benzylidene hydrazones (3a-p) were synthesized. Structures of the title compounds were determined by analytical and spectral methods. 3a-p were evaluated for antituberculosis activity against Mycobacterium tuberculosis H37Rv. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.