Therapeutic Potential of Adjuvant Stereotactic Body Radiotherapy for Gallbladder Cancer

Mahadevan A., Dagoglu N., Tseng J. F., Khawaja K., Evenson A.

CUREUS, vol.7, no.8, 2015 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 8
  • Publication Date: 2015
  • Doi Number: 10.7759/cureus.299
  • Journal Name: CUREUS
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals
  • Istanbul University Affiliated: Yes


Surgical treatment remains the only curative treatment for gallbladder cancer. However, even after liver resection, locoregional failure seems to be a significant problem. While there is no Level I evidence, multiple studies have shown benefit for adjuvant radiation in high-risk patients. After extensive liver resection, tolerance to conventional chemoradiation may be limited by potential liver toxicity. Stereotactic body radiotherapy has been used safely and effectively in hepatobiliary malignancies. We present a case report, highlighting the potential therapeutic role of adjuvant stereotactic body radiotherapy (SBRT) for gallbladder cancer.