Prostate-specific antigen flare induced by cabazitaxel-based chemotherapy in patients with metastatic castration-resistant prostate cancer


Angelergues A., Maillet D., Flechon A., Ozguroglu M. , Mercier F., Guillot A., ...Daha Fazla

EUROPEAN JOURNAL OF CANCER, cilt.50, ss.1602-1609, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 50 Konu: 9
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.ejca.2014.03.015
  • Dergi Adı: EUROPEAN JOURNAL OF CANCER
  • Sayfa Sayıları: ss.1602-1609

Özet

Background: A prostate-specific antigen (PSA) flare occurs in about 15% of metastatic castration-resistant prostate cancer (mCRPC) patients receiving docetaxel. This flare has no standard definition. Its impact on treatment efficacy is unclear. We sought to evaluate the incidence and characteristics of PSA flare on cabazitaxel, and its impact on survival.