Impact of High-Intensity Interval Training on Bone Metabolism and the Metabolic and Hormonal Profiles of Postmenopausal Women


Yarış S., Yetgin M. K., AGOPYAN A., Çakır Ö. K., Gedikbasi A., bulut h., ...Daha Fazla

İstanbul Medical Journal, cilt.26, sa.1, ss.5-10, 2025 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 1
  • Basım Tarihi: 2025
  • Doi Numarası: 10.4274/imj.galenos.2024.08505
  • Dergi Adı: İstanbul Medical Journal
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.5-10
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: Although many forms of exercise are known to have positive effects on bone metabolism in postmenopausal women, the effect of high-intensity interval training (HIIT) has not been investigated in this setting. This study aimed to evaluate the impact of the 6-week HIIT program on body composition, biochemical parameters, and bone turnover markers in overweight and obese postmenopausal women. Methods: A total of 32 postmenopausal women were randomly assigned to exercise (n=15) or control (n=17) groups. The blood samples and body composition were analyzed. The exercise group participated in a 6-week stationary bike HIIT exercise [(3 days/week; 30 sec work-90 sec resting intervals with 90-95% of the heart rate reserve-12 to 16 min/day)]. The control group was not involved in any exercise program. Results: In the exercise group, significant reductions were noted in waist and hip circumference, low-density lipoprotein, total cholesterol, triglycerides, phosphorus, calcium, albumin, bone-specific alkaline phosphatase, type 1 collagen C-terminal telopeptide, and osteocalcin levels, in addition to significant increases in high-density lipoprotein, free thyroxine, thyroid-stimulating hormone, vitamin D (25-hidroksi vitamin D), and cortisol levels, when compared with the control group (p<0.05). Conclusion: Our findings revealed the positive effects of the 6-week HIIT training program in postmenopausal women in terms of reduction in waist and hip circumference, improvement in lipid and hormonal profile, and maintenance of bone metabolism. According to our findings, the 6-week stationary bike HIIT exercise was safe and beneficial for postmenopausal women’s health.