Relationship between vitamin B12, homocysteine and oxidative stress in juvenile idiopathic arthritis


Bicer N. C., Aksoydan E., Zeybek C. A., Barut K., Kasapcopur O.

MEDICAL JOURNAL OF BAKIRKOY, vol.12, no.1, pp.1-10, 2016 (ESCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 12 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.5350/btdmjb201612101
  • Journal Name: MEDICAL JOURNAL OF BAKIRKOY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1-10
  • Istanbul University Affiliated: Yes

Abstract

Juvenile idiopathic arthritis (JIA), which is one of the rheumatic diseases, is a systemic inflammatory disease characterized by chronic and erosive synovitis that involves peripheral joints. In patients who had been diagnosed with JIA, increasing proinflammatory cytokines, metabolic abnormalities associated with systemic inflammation, may provoke vascular endothelial damage which can cause atherosclerosis.