Autoimmune thyroid encephalopathy presenting with epilepsia partialis continua

AYDIN-OEZEMIR Z., Tuezuen E., BAYKAN B., Akman-Demir G., OEZBEY N., GUERSES C., ...Daha Fazla

CLINICAL EEG AND NEUROSCIENCE, cilt.37, sa.3, ss.204-209, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1177/155005940603700308
  • Dergi Adı: CLINICAL EEG AND NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.204-209
  • Anahtar Kelimeler: Hashimoto's disease, status epilepticus, thyroid encephalopathy, HASHIMOTOS ENCEPHALOPATHY, ANTIBODIES, DISEASE
  • İstanbul Üniversitesi Adresli: Evet

Özet

We report the first case of an autoimmune thyroid encephalopathy presenting with multifocal motor status epilepticus. A 37-year-old female patient was admitted with multifocal motor seizures intractable to intravenous status epilepticus treatments, asymmetrical quadriparesis, truncal ataxia and continuous semi-rhythmical jerks. Pathological signal alterations were detected in both precentral cortices in MRI examination. Autoimmune thyroiditis was diagnosed after radiological examinations of the thyroid gland and thyroid function tests. Seizures promptly ceased following intravenous steroid treatment. Immunohistochemistry studies showed mild to moderate neuronal staining with the plasma and CSF samples. Remarkably, autoimmune thyroiditis may present with migrating focal motor status epilepticus. We recommend anti-thyroid antibody screening for multifocal motor status epilepticus cases of unspecified cause.