Functional connectivity disturbances of ascending reticular activating system and posterior thalamus in juvenile myoclonic epilepsy in relation with photosensitivity: A resting-state fMRI study


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Ur Özçelik E., Kurt E., Şirin N. G., Eryürek K., Ulaşoglu Yıldız Ç., Harı E., ...More

EPILEPSY RESEARCH, vol.171, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 171
  • Publication Date: 2021
  • Doi Number: 10.1016/j.eplepsyres.2021.106569
  • Journal Name: EPILEPSY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Abstracts in Social Gerontology, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Keywords: Juvenile myoclonic epilepsy, Ascending reticular activating system, rResting-state fMRI, Photosensitivity, Posterior thalamus, Locus coeruleus
  • Istanbul University Affiliated: Yes

Abstract

Objective: Juvenile myoclonic epilepsy (JME) is typified by the occurrence of myoclonic seizures after awakening, though another common trait is myoclonic seizures triggered by photic stimulation. We aimed to investigate the functional connectivity (FC) of nuclei in the ascending reticular activating system (ARAS), thalamus and visual cortex in JME with and without photosensitivity.