Acute hepatitis B despite a previous high titer of anti-HBs


Ozaras R., Ar C., Ongoren S., Mete B., Tabak F., Mert A., ...Daha Fazla

HEPATOLOGY INTERNATIONAL, cilt.4, sa.2, ss.530-532, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4 Sayı: 2
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1007/s12072-010-9177-3
  • Dergi Adı: HEPATOLOGY INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.530-532
  • İstanbul Üniversitesi Adresli: Evet

Özet

Loss of HBsAg and development of surface and core antibodies represent clinical cure. However, recent evidence suggests that hepatitis B virus (HBV) persists in a latent state even in those with mounted protective antibodies. After significant immunosuppression, anti-HBs may decrease and HBsAg may reappear (reverse seroconversion). Reverse seroconversion of HBV has been observed in association with hematopoietic stem cell transplantation, renal transplantation, intensive chemotherapy, human immunodeficiency infection, or rituximab usage.