Potent colon cancer cell line toxicity of the fruit extracts of Heptaptera triquetra (Vent.) Tutin

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Tosun F., MİSKİ M.

Acta Pharmaceutica Sciencia, cilt.60, sa.3, ss.295-299, 2022 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.23893/1307-2080.aps.6019
  • Dergi Adı: Acta Pharmaceutica Sciencia
  • Derginin Tarandığı İndeksler: Scopus, EMBASE
  • Sayfa Sayıları: ss.295-299
  • Anahtar Kelimeler: Apiaceae, Cytotoxic activity, Heptaptera triquetra
  • İstanbul Üniversitesi Adresli: Evet

Özet

© 2022, Istanbul Medipol University. All rights reserved.Cytotoxic activities of the fruit extracts of Heptaptera triquetra (Vent.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the fruits of H. triquetra showed the highest cytotoxic activities with IC50 values of 9.3 and 5.3 ug/mL on the COLO205 and KM12 cell lines, respectively. Whereas, the ethyl acetate extract of the fruits showed moderate cytotoxic activity with IC50 values of 22.3 ug/mL against the KM12 cell lines.