Efficacy and tolerability of fixed, low-dose combination therapy with verapamil sustained-release and trandolapril in patients with mild to severe essential hypertension uncontrolled by monotherapy: An open-label, multicenter trial

Adalet, Kamil; Oflaz, H; Sezer, A; Buyukozturk, K

doi:10.1016/s0011-393x(01)80010-2

Efficacy and tolerability of fixed, low-dose combination therapy with verapamil sustained-release and trandolapril in patients with mild to severe essential hypertension uncontrolled by monotherapy: An open-label, multicenter trial

Atıf İçin Kopyala

Adalet K., Oflaz H., Sezer A., Buyukozturk K.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.62, sa.4, ss.261-271, 2001 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 62 Sayı: 4
Basım Tarihi: 2001
Doi Numarası: 10.1016/s0011-393x(01)80010-2
Dergi Adı: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.261-271
İstanbul Üniversitesi Adresli: Evet

Özet

Background: Only 40% to 60% of patients with essential hypertension respond adequately to antihypertensive monotherapy. The combination of an angiotensin-converting enzyme inhibitor and a calcium antagonist, both of which have tissue-protective properties but different mechanisms of action, may lead to an additive antihypertensive effect.