Correlation of laboratory parameters and Chest CT findings in young adults with COVID-19 and comparison of imaging findings with children*

Bayramoglu Z., Cingoz E., Comert R. G., Gasimli N., Kaba O., Yanartas M. S., ...Daha Fazla

CLINICAL IMAGING, cilt.79, ss.265-272, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 79
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.clinimag.2021.06.012
  • Dergi Adı: CLINICAL IMAGING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Biotechnology Research Abstracts, Compendex, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.265-272
  • Anahtar Kelimeler: COVID-19, Computed tomography, Children, Young adults, DISEASE 2019 COVID-19, FEATURES, INFECTION
  • İstanbul Üniversitesi Adresli: Evet

Özet

Purpose: We aimed to compare COVID-19 imaging findings of young adults (19-35 years of age) with those of children (0-18 years) and to correlate imaging findings of young adults with their laboratory tests. Materials and methods: This retrospective study included Real Time-Polymerase Chain Reaction (RT-PCR) confirmed 130 young adults (mean age: 28.39 +/- 4.77; 65 male, 65 female) and 36 children (mean age: 12.41 +/- 4.51; 17 male, 19 female), between March and June 2020. COVID-19 related imaging findings on chest CT were examined in young adults and compared with children by the Mann-Whitney U, and Chi-square or Fisher's exact test. Laboratory examinations of young adults were assessed in terms of correlation with radiological findings by the Spearman's correlation analysis. Results: Bilateral multiple distributions (p = 0.014), subpleural involvement, and pleural thickening (p = 0.004), GGOs with internal consolidations were more frequent in adults (p = 0.009). Infiltrations were significantly larger than 20 mm in young adults (p = 0.011). The rates of feeding vessel sign, vascular enlargement, and halo sign were significantly higher in young adults (p < 0.003). Highly significant positive correlations were found between radiological and biochemical parameters. Conclusion: Distribution, size, and pattern of COVID-19 related imaging findings differed in children and young adults. Radiological findings were correlated with biochemical parameters but not with blood count results of young adults.