Direct Inhibition of Renin

Uresin Y., Ozunal Z. G.

TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI, cilt.27, ss.82-84, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 27
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1038/nrneph.2009.201
  • Dergi Adı: TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.82-84
  • İstanbul Üniversitesi Adresli: Evet

Özet

From the beginning of the history of renin angiotensin system (RAS) with the renal extracts in 1898 it still continues to be exciting. After angiotensin converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARBs), direct renin inhibitors (DRI) recently entered the RAS arena. With the increasing evidence, RAS inhibition is an important treatment strategy in hypertension. Results of ongoing and future clinical trials with specific populations and focusing on protection of end-organ damage will enrich our knowledge and understanding on direct renin inhibition.