Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised

Janssen H., van Zonneveld M., Senturk H., Zeuzem S., Akarca U., Cakaloglu Y., ...More

LANCET, vol.365, no.9454, pp.123-129, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 365 Issue: 9454
  • Publication Date: 2005
  • Doi Number: 10.1016/s0140-6736(05)17701-0
  • Journal Name: LANCET
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.123-129
  • Istanbul University Affiliated: No


Background Treatment of HBeAg-positive patients with chronic hepatitis B is not effective in most. A combination of immunomodulatory pegylated interferon alfa-2b and antiviral lamivudine might improve the rate of sustained response.