Association of ADIPOQ C-11377G (rs266729), TNF-alpha G-308A (rs1800629) and TNF-alpha G-238A (rs361525) Single Nucleotide Polymorphisms with Type 2 Diabetes Mellitus in Pakistani Population


Nadeem A., Mumtaz S., Naveed A. K., Mansoor Q., Aslam M., Ismail M.

JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, vol.27, no.10, pp.625-630, 2017 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 10
  • Publication Date: 2017
  • Journal Name: JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.625-630
  • Keywords: Adiponectin, Tumor necrosis factor-alpha, Single nucleotide polymorphism, Diabetes mellitus, NECROSIS-FACTOR-ALPHA, METABOLIC SYNDROME, ADIPONECTIN POLYMORPHISMS, SERUM ADIPONECTIN, PROMOTER VARIANTS, FATTY-ACIDS, OBESITY, IDENTIFICATION, INDIVIDUALS, PROTEIN
  • Istanbul University Affiliated: No

Abstract

Objective: To determine the frequencies of adiponectin (ADIPOQ) C-11377G, tumor necrosis factor-alpha (TNF-alpha) G-308A and TNF-alpha G-238A single nucleotide polymorphisms (SNP) and their association with serum levels in Pakistani T2DM and healthy population.