Cardioactive Diterpenes from the roots of Salvia eriophora

ULUBELEN A., Birman H., OKSUZ S., TOPCU G., KOLAK U., BARLA A., ...Daha Fazla

PLANTA MEDICA, cilt.68, sa.9, ss.818-821, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Sayı: 9
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1055/s-2002-34408
  • Dergi Adı: PLANTA MEDICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.818-821
  • Anahtar Kelimeler: Salvia eriophora, Lamiaceae, abietane and rearranged abietane diterpenes, vasodepressor effect, QUINONES
  • İstanbul Üniversitesi Adresli: Evet

Özet

From the roots of Salvia eriophora (Lamiaceae), a new compound, 4,14-dhydroxysaprorthoquinone, was isolated in addition to ten known diterpenoids. The structure of the new compound was established by spectroscopic analysis. The crude extract of the plant and the isolated diterpenoids were tested for their cardiovascular activities using Wistar Albino rats. Activity was demonstrated in the crude extract and in 4,14-dihydroxysaprorthoquinone, aethiopinone, ferruginol, 4,12-dihydroxysapriparaquinone, and 6,7-dehydroroyleanone.