Nitric oxide mediated effects of nebivolol in cardiorenal syndrome


Mercanoglu G., Semen O.

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, cilt.22, ss.1314-1324, 2019 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 22 Konu: 11
  • Basım Tarihi: 2019
  • Doi Numarası: 10.22038/ijbms.2019.37400.8927
  • Dergi Adı: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Sayfa Sayıları: ss.1314-1324

Özet

Objective(s): Despite several proposed mechanisms for the pathophysiology of cardiorenal syndrome (CRS), the exact mechanism remains unclear. Nitrosative stress has been argued as a key mechanism recently. Nebivolol is a beta-blocker with nitric oxide (NO)-releasing effect. In the present study, NO-mediated effects of two different treatment regimes of nebivolol in CRS were studied.