Akademik Veri Yönetim Sistemi
Turkish Association of Oral and Maxillofacial Surgery 26th International Scientific Congress, Girne, Kıbrıs (Kktc), 28 Nisan - 02 Mayıs 2019, ss.204-205
Bisphosphonates are used to treat osteoporosis or to inhibit bone metastasis in cancer patients and
in Paget’s disease. Use of these medications may cause necrotic areas in jaw bones where intense
remodelation occurs. MRONJ mostly seen in intravenous route, oral route is known as safer. In
following case 75-year-old female patient administered our clinic with complaint of jaw pain and
difficulty in nutrition. She had only osteoporosis with no other disease, but her general situation
wasn’t quite good. It is learnt that she ibandronic acid for 4 years with oral route. In intraoral
examination bone necrosis with purulent leakage was seen at left posterior mandible. Patient take
1.200,00 EU Penicillin V 2 tablets for a day along 2 weeks. In control session there was no notable
recovery, so 500 mg Ornidazole is added to antibiotherapy. End of one month there wasn’t any
recovery but also patient started to have gastrointestinal problems due to antibiotic use for 4
months. For that, antibiotherapy was totally finished and essential oil protocol which includes
myrrh, coconut oil, palmrosa,neem and niaouli oils was initiated. In one week control session,
purulent leakage decreased and mucosal recovery was noted. Patient perform this protocol for 3
month and as a consequence infection pacificated and patient is prevented for any gastrointestinal
complication due to antibiotic use.