Determination of Dissociation Constants of Some Hydroxylated Benzoic and Cinnamic Acids in Water from Mobility and Spectroscopic Data Obtained by CE-DAD

Ozkorucuklu S., BELTRAN J. L., FONRODONA G., BARRON D., Alsancak G., BARBOSA J.

JOURNAL OF CHEMICAL AND ENGINEERING DATA, cilt.54, sa.3, ss.807-811, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1021/je800595x
  • Dergi Adı: JOURNAL OF CHEMICAL AND ENGINEERING DATA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.807-811
  • İstanbul Üniversitesi Adresli: Hayır

Özet

In this study, the dissociation constants of a series of phenolic acids, including benzoic acid, four hydroxylated derivatives (p-hydroxybenzoic, protocatechuic, vanillic, and gallic), and four hydroxylated cinnamic acid derivatives (p-coumaric, caffeic, ferulic, and sinapinic) have been determined in water by capillary electrophoresis (CE) from the electrophoretic mobilities at different pH value. The pK(a) values have also been obtained from the absorbance spectra at the maximum of the electrophoretic peaks, which were measured with a diode-array detector (CE-DAD methodology). The pK(a) values obtained from both methodologies (CE and CE-DAD) have been compared with those previously published in the literature and also with the values predicted by the SPARC online pK(a) calculator.