Indomethacin-induced Colon Perforation in Bartter's Syndrome
INDIAN JOURNAL OF PEDIATRICS, cilt.76, sa.3, ss.322-323, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 76 Sayı: 3
- Basım Tarihi: 2009
- Doi Numarası: 10.1007/s12098-009-0062-9
- Dergi Adı: INDIAN JOURNAL OF PEDIATRICS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.322-323
- İstanbul Üniversitesi Adresli: Evet
Özet
Bartter's syndrome (BS) is an inherited renal tubular disorder characterized by hypokalemia, hypochloremic metabolic alkalosis, and hyperaldosteronism with normal blood pressure. A 22-year-old woman was referred at 23 week of gestation. Polyhydramnios was detected and the chloride level of the amniotic fluid was high. The mother was treated with indomethacin from 26 to 31 week of gestation. The newborn was delivered at 34 week of gestation. At 8th day of life, indomethacin was also started for the baby. After three days, a colonic perforation developed. Indomethacin-induced colon perforation is uncommon in antenatal Bartter's syndrome. This patient indicates that administration of indomethacin in both antenatal and/or early postnatal period may be associated with colonic perforation. [Indian J Pediatr 2009; 76 (3) : 322-323] E-mail: drcivilibal@hotmail.com