Antidiabetic drug metformin is effective on the metabolism of asymmetric dimethylarginine in experimental liver injury

Bal, Fatih; Bekpinar, Seldağ; Unlucerci, Yesim; Kusku-Kiraz, Zeynep; Onder, Semen; Uysal, Mujdat; Gurdol, Figen

doi:10.1016/j.diabres.2014.08.028

Antidiabetic drug metformin is effective on the metabolism of asymmetric dimethylarginine in experimental liver injury

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Bal F., Bekpinar S., Unlucerci Y., Kusku-Kiraz Z., Onder S., Uysal M., ...More

DIABETES RESEARCH AND CLINICAL PRACTICE, vol.106, no.2, pp.295-302, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 106 Issue: 2
Publication Date: 2014
Doi Number: 10.1016/j.diabres.2014.08.028
Journal Name: DIABETES RESEARCH AND CLINICAL PRACTICE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.295-302
Istanbul University Affiliated: Yes

Abstract

Aims: We aimed to investigate the pharmacological efficiency of metformin on asymmetric dimethylarginine (ADMA) metabolism in inflammation caused by the lipopolysaccharide (LPS)/D-galactosamine (D-GalN) treatment.