Common MEFV mutations and polymorphisms in an elderly population: an association with E148Q polymorphism and rheumatoid factor levels


Turanli E. T., Beger T., Erdincler D., Curgunlu A., Karaman S., Karaca E., ...More

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.27, no.2, pp.340-343, 2009 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 2
  • Publication Date: 2009
  • Journal Name: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.340-343
  • Keywords: FMF, MEFV E148Q polymorphism, inflammation, elderly population, rheumatoid factor, FAMILIAL MEDITERRANEAN FEVER, GENE-MUTATIONS, BEHCETS-DISEASE, PREVALENCE, INFLAMMATION, PREDISPOSE, FREQUENCY
  • Istanbul University Affiliated: Yes

Abstract

Objectives. To analyse the most common MEFV (Mediterranean fever gene) mutations and polymorphisms in an elderly population free of chronic inflammatory disease (n=764), and explore possible associations between hsCRP (high sensitive C-reactive protein) and RF (rheumatoid factor) levels with MEFV mutations and polymorphisms.