Could the "Stiff Rim Sign" Be an Indicator of Lysyl Oxidase Activity in Breast Cancer?

Kayadibi Y., Kilic F., KARATAŞ Ö. F., Ilvan S., Esmerer E. U., Kayadibi T., ...More

IRANIAN JOURNAL OF RADIOLOGY, vol.16, no.3, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.5812/iranjradiol.84157
  • Journal Name: IRANIAN JOURNAL OF RADIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Istanbul University Affiliated: Yes

Abstract

Background: Shear wave elastography (SWE) is a non-invasive and easily applicable imaging modality, which can provide quantitative information of tissue stiffness. Peritumoral high SWE elasticity values (stiff rim sign) has been reported in many studies. Lysyl oxidase (LOX) enzyme is implicated in the formation of peri-tumoral stiffness.