Wet towels which seemed unfamiliar at the begining has begun to become an irresistable part of our daily life as the convenience of its use is seen. They are with us every where; on trips, in the restaurants, in public areas, at the hospitals, in bags, in our pockets. However, how much can these wet towels protect us from the microorganisms that exist widely in nature and can infect us with various ways? Based on this idea, using the European Standard EN 1276 method, the activities of wet towels produced in our country containing antimicrobiological substances that are effective on the hand antisepsis and surface disinfection against several microorganisms have been studied. Suspensions of 10(7)cfu/mL have been used in these experiments and a ratio of at least 99.98 % killing have been observed. We have seen that the wet towels that are used in hand antisepsis and surface disinfection are effective against all tested microorganisms except bacterial spores and it is evident that these towels, with the safety they have and the confindence they give us, will be with us for a long time and will not be out of our life very easily.