The variations of BOP gene in hypertrophic cardiomyopathy.

Abaci N., Gulec Ç., Bayrak F., Komurcu-Bayrak E., KAHVECI G., Erginel-Unaltuna N.

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, cilt.10, sa.4, ss.303-9, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.5152/akd.2010.087
  • Dergi Adı: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.303-9
  • Anahtar Kelimeler: BOP, hypertrophic cardiomyopathy, clinical heterogeneity, modifying gene, genetic variation, QT dispersion, QT DISPERSION, VENTRICULAR REPOLARIZATION, HETEROGENEOUS EXPRESSION, POTASSIUM CHANNELS, SUDDEN-DEATH, K+ CURRENTS, MOUSE CD8B, HEART, ARRHYTHMIAS, MYOCARDIUM
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: The observation that Bop null allele mice show underdeveloped right ventricle and excessive development of left ventricle, suggests the possible relationship between human BOP gene and hypertrophic cardiomyopathy (HCMP). In our study, we investigated this possible relationship between BOP gene variations and QT dispersion, a noninvasive arrhythmic risk marker for HCMP.