ISTANBUL MEDICAL JOURNAL, cilt.18, sa.1, ss.23-27, 2017 (ESCI)
Objective: Vitamin D is a key regulator of calcium homeostasis and has anti-inflammatory and immunomodulatory effects. Active vitamin D has a direct effect on T cells and antigen-presenting cells. It also suppresses the differentiation of B cells to plasma cells and inhibits immunoglobulin production. Vitamin D supplementation is associated with a favorable outcome in chronic inflammatory diseases. In this study, we aimed to determine serum vitamin D levels in patients with acute toxic, ischemic, or viral hepatitis and whether the levels had an effect on clinical progression or mortality in patients with acute hepatitis.