Association between genetic variants in glutathione peroxidase 1 (GPx1) gene, GPx activity and the risk of prostate cancer

Kucukgergin C., Gokpinar M., Sanli O., Tefik T., Oktar T. M., Seckin S.

MINERVA UROLOGICA E NEFROLOGICA, vol.63, no.3, pp.183-190, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 3
  • Publication Date: 2011
  • Journal Name: MINERVA UROLOGICA E NEFROLOGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.183-190
  • Keywords: Prostate cancer, Glutathione peroxidase GPX1, Genetic diseases, inborn
  • Istanbul University Affiliated: Yes

Abstract

Aim. The Aim of this study was to investigate the association between GPx1 Pro198Leu polymorphism with the development and progression of prostate cancer (PCa) and evaluate whether smoking status and advanced age could modify this association.