Tenofovir disoproxil fumarate has a substantial efficacy against multidrug-resistant strains of hepatitis B virus

Baran, Bulent; Soyer, Ozlem; Ormeci, Aslı; Gokturk, Suut; Evirgen, Sami; Akyuz, Filiz; Karaca, Cetin; Demir, Kadir; Besisik, Selman; Onel, Derya; Gulluoglu, Mine; Badur, Selim; Kaymakoglu, Sabahattin

doi:10.1111/liv.12831

Tenofovir disoproxil fumarate has a substantial efficacy against multidrug-resistant strains of hepatitis B virus

Baran B., Soyer O. M., Ormeci A., Gokturk S., Evirgen S., Akyuz F., ...Daha Fazla

LIVER INTERNATIONAL, cilt.35, sa.10, ss.2265-2274, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 35 Sayı: 10
Basım Tarihi: 2015
Doi Numarası: 10.1111/liv.12831
Dergi Adı: LIVER INTERNATIONAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.2265-2274
Anahtar Kelimeler: adefovir failure, chronic hepatitis B, genotypic resistance, tenofovir disoproxil fumarate, ADEFOVIR DIPIVOXIL, LAMIVUDINE TREATMENT, TREATMENT FAILURE, NAIVE PATIENTS, THERAPY, MONOTHERAPY, HBV, EMTRICITABINE, POLYMERASE, SAFETY
İstanbul Üniversitesi Adresli: Evet

Özet

Background & AimsTo evaluate the efficacy of tenofovir in chronic hepatitis B (CHB) patients with adefovir resistance (ADF-R) and suboptimal response to adefovir (ADF-S).