Use of Etests with carbapenems for Gram-negative rods producing beta-lactamases

Kocazeybek, S; Arabaci, U

doi:10.1016/s0924-8579(01)00487-3

Use of Etests with carbapenems for Gram-negative rods producing beta-lactamases

Atıf İçin Kopyala

Kocazeybek S., Arabaci U.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, cilt.19, sa.2, ss.159-162, 2002 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 19 Sayı: 2
Basım Tarihi: 2002
Doi Numarası: 10.1016/s0924-8579(01)00487-3
Dergi Adı: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.159-162
İstanbul Üniversitesi Adresli: Hayır

Özet

The in vitro activity of imipenem and meropenem on strains of Gram-negative rods producing extended-spectrum beta-lactamase (ESBL) and inducible beta-lactamase (IBL) was studied using the Etest. In all, 185 strains from the surgical intensive care units of four different hospitals were looked at over 2 years. Of these, 94 were ESBL producers and 91 were IBL positive. The in vitro sensitivities of imipenem and meropenem were 89.7 and 95.1%, respectively, against all strains. The imipenem and meropenem sensitivities of Klebsiella spp. were 98.4 and 100%, respectively, but imipenem resistance (21.6%) in Pseudomonas aeruginosa strains was higher than that of meropenem (10.8%). (C) 2002 Elsevier Science B.V. and the International Society of Chemotherapy. All rights reserved.