Assoc. Prof.Zeynep Gamze GÜVEN


Aziz Sancar Institute of Experimental Medicine, Department of Genetics


Research Areas: Life Sciences, Molecular Biology and Genetics, Genetic Disorders, Genomics, Natural Sciences

Metrics

Publication

53

Citation (WoS)

430

Citation (Scopus)

444

H-Index (WoS)

9

H-Index (Scopus)

9

Project

14

Open Access

2
UN Sustainable Development Goals

Education Information

2010 - 2016

2010 - 2016

Doctorate

Istanbul University, Health Sciences Institute, Genetik, Turkey

2005 - 2008

2005 - 2008

Postgraduate

Istanbul University, Health Sciences Institute, Genetik, Turkey

2000 - 2004

2000 - 2004

Undergraduate

Istanbul University, Faculty Of Science, Biyoloji, Turkey

Dissertations

2016

2016

Doctorate

Geç ve erken başlangıçlı Alzheimer hastalığında rol oynayan miRNAların incelenmesi

Istanbul University, Health Sciences Institute, Genetik

2008

2008

Postgraduate

Non spesifik mental retardasyon olgularında FMR1 etkileşimli sitoplazmik protein 1 ve 2 (CYFIP1 ve CYFIP2) genlerinin incelenmesi

Istanbul University, Health Sciences Institute, Genetik

Foreign Languages

B2 Upper Intermediate

B2 Upper Intermediate

English

Certificates, Courses and Trainings

2020

2020

ORPHEUS Süreci ve Danışmanlık Eğitimi Kursu

Vocational Course

İstanbul Üniversitesi Sürekli Eğitim Uygulama ve Araştırma Merkezi

2019

2019

Klinisyenler için Nöroimmünolojide Kullanılan Araştırma Yöntemleri

Health&Medicine

Nöroimmünoloji derneği

2018

2018

İş sağlığı ve Güvenlği

Occupational Health and Safety

İstanbul Üniversitesi Sürekli Eğitim Uygulama ve Araştırma Merkezi

2015

2015

4th Hybrid Course in Next Generation Sequencing

Health&Medicine

European School of Genetic Medicine

2013

2013

Hybrid Course in Next Generation Sequencing

Health&Medicine

European School of Genetic Medicine

2010

2010

Stratejik Yönetimin Temel Kavramları Programı

Project Management

İstanbul Proje Yönetim Derneği

2010

2010

MPM-19 Proje Yönetimi Eğitimi

Project Management

İstanbul Proje Yönetim Derneği

2010

2010

Applied Molecular Methods

Health&Medicine

Istanbul Universitesi Deneysel Tıp Araştırma Enstitüsü

2006

2006

Clinico-Genetic training on Spinocerebellar Ataxias

Health&Medicine

İstanbul Üniversitesi ve EUROSCA

2006

2006

Koruyucu Genetik Tanı Eğitimi-III

Health&Medicine

Vehbi Koç Vakfı Amerikan Hastanesi

Research Areas

Life Sciences, Molecular Biology and Genetics, Genetic Disorders, Genomics, Natural Sciences

Academic Titles / Tasks

2009 - Continues

2009 - Continues

Lecturer PhD

Istanbul University, Aziz Sancar Institute Of Experimental Medicine, Department Of Genetics

2014 - 2014

2014 - 2014

Expert

University College London, Institute Of Neurology, Molecular Neuroscience

2013 - 2013

2013 - 2013

Expert

University College London, Institute Of Neurology, Molecular Neuroscience

2013 - 2013

2013 - 2013

Expert

University College London, Institute Of Neurology, Molecular Neuroscience

Taught Courses And Trainings

2019 - 2019

2019 - 2019

III.Deneysel Sinirbilim Yöntemleri Kursu-Teorik ve Uygulamalı Nörogenetik

Academic Units - Course

Güven Z. G. , İplik E. S. , Şanlı E., Ergül E., Küçükali C. İ. , Tüzün E., et al.

Published journal articles indexed by SCI, SSCI, and AHCI

2021

2021

TREM2 variants as a possible cause of frontotemporal dementia with distinct neuroimaging features.

Samanci B., Bilgiç B., Gelişin Ö., Tepgeç F., Guven G. , Tüfekçioğlu Z., et al.

European journal of neurology, vol.28, no.8, pp.2603-2613, 2021 (Peer-Reviewed Journal) identifier identifier identifier

2021

2021

Comprehensive analysis of copy number variation in a Turkish dementia cohort

Dehghani N., Güven Z. G. , Kun-Rodrigues C., Gouveia C., Foster K., Hanağası H. A. , et al.

HUMAN GENOMICS, vol.15, no.48, pp.1-12, 2021 (Journal Indexed in SCI Expanded)

2021

2021

A novel PSEN2 p.Ser175Phe variant in a family with Alzheimer's disease

Guven G., Samancı B., Güleç Ç., Hanagasi H., Gürvit İ. H. , Gokalp E. E. , et al.

NEUROLOGICAL SCIENCES, vol.42, no.6, pp.2497-2504, 2021 (Peer-Reviewed Journal) identifier identifier identifier

2020

2020

Peripheral TREM2 mRNA levels in early and late-onset Alzheimer disease's patients.

Guven G. , BİLGİÇ B. , SAMANCI B. , GÜRVİT İ. H. , Hanagasi H. A. , Donmez C., et al.

Molecular biology reports, vol.47, no.8, pp.5903-5909, 2020 (Peer-Reviewed Journal) identifier identifier identifier

2020

2020

The association of serum clusterin levels and Clusterin rs11136000 polymorphisms with Alzheimer disease in a Turkish cohort

Guven G. , Ozer E., Bilgiç B. , Hanagasi H. , Gurvit H. , Lohmann E., et al.

NEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY, vol.37, no.3, pp.134-141, 2020 (Peer-Reviewed Journal) identifier identifier

2018

2018

HPCA Confirmed as a Genetic Cause of DYT2-Like Dystonia Phenotype

Atasu B., Hanagasi H. A. , Bilgic B. , Pak M., Erginel-Unaltuna N. , Hauser A., et al.

MOVEMENT DISORDERS, vol.33, no.8, pp.1354-1358, 2018 (Peer-Reviewed Journal) identifier identifier identifier

2017

2017

Mutations in TYROBP are not a common cause of dementia in a Turkish cohort

Darwent L., Carmona S., Lohmann E., GUVEN G. , Kun-Rodrigues C., Bilgic B. , et al.

Neurobiology of Aging, vol.58, 2017 (Journal Indexed in SCI Expanded) identifier identifier identifier

2016

2016

A novel homozygous DJ1 mutation causes parkinsonism and ALS in a Turkish family

Hanagasi H. A. , Giri A., Kartal E., Guven G. , Bilgic B. , Hauser A., et al.

PARKINSONISM & RELATED DISORDERS, vol.29, pp.117-120, 2016 (Journal Indexed in SCI) identifier identifier identifier

2015

2015

A new F-box protein 7 gene mutation causing typical Parkinson's disease

Lohmann E., COQUEL A., HONORE A., Gurvit H. , Hanagasi H. A. , Emre M., et al.

MOVEMENT DISORDERS, vol.30, no.8, pp.1130-1133, 2015 (Peer-Reviewed Journal) identifier identifier identifier

2015

2015

Clinical variability in ataxia-telangiectasia

LOHMANN E., KRUEGER S., HAUSER A., Hanagasi H. A. , Guven G. , Erginel-Unaltuna N. , et al.

JOURNAL OF NEUROLOGY, vol.262, no.7, pp.1724-1727, 2015 (Journal Indexed in SCI) identifier identifier identifier

Articles Published in Other Journals

2021

2021

ERKEN VE GEÇ BAŞLANGIÇLI ALZHEIMER HASTALARININ PERİFERİK KANLARINDA SEÇİLMİŞ miRNA’LARIN ANLATIM DÜZEYİ

Güven Z. G. , Lohmann E., Güleç Ç. , Bilgiç B. , Özer E., Hanağası H. A. , et al.

İstanbul Tıp Fakültesi Dergisi , vol.84, no.2, pp.165-174, 2021 (National Refreed University Journal)

2016

2016

15 Yıllık Huntington Hastalığı Genetik Test Sonuçları ve Literatürdeki HH Test Kılavuzları

BAYRAK A. E. , PODA M. , GÜVEN Z. G. , GEYİK F. , ÇOBAN N. , GÜLEÇ Ç. , et al.

Deneysel Tıp Araştırma Enstitüsü Dergisi, vol.4, no.10, pp.10-16, 2016 (Peer-Reviewed Journal)

Refereed Congress / Symposium Publications in Proceedings

2021

2021

Plazminojen Aktivatör İnhibitör-1 (PAI-1) 4g/5g Gen Polimorfizminin Alzheimer Hastalığı Riski Üzerine Etkisi

Güven Z. G. , Samancı B.

6. Uluslararası Tıp ve Sağlık Bilimleri Araştırmaları Kongresi, Ankara, Turkey, 10 - 11 April 2021, pp.526

2020

2020

Analysis of copy number variation in a Turkish dementia cohort

Dehghani N., Kun-Rodrigues C., Foster K., Hanağası H. A. , Lohmann E., Güven Z. G. , et al.

Alzheimer's Association International Conference (AAIC) , 27 - 31 July 2020, pp.44868

2018

2018

Cholesterol related gene polymorphisms in Alzheimer Disease

Güven Z. G. , Vurgun E., Bilgiç B., Hanağası H. A. , Gürvit İ. H. , Lohmann E., et al.

European Human Genetics Conference 2018, Milan, Italy, 16 - 19 June 2018, pp.1

2019

2019

ERKEN BAŞLANGIÇLI ALZHEIMER HASTALARINDA PSEN1 GENİ MUTASYON TARAMASI

Güven Z. G. , Bilgiç B.

9. Ulusal Alzheimer Kongresi, Ankara, Turkey, 2 - 04 May 2019, pp.1

2019

2019

Is MTHFR C677T polymorphism risk factor for Turkish Alzheimer Disease’s patients?

Güven Z. G. , Bilgiç B.

13. Balkan Genetics Congress of Human Genetics, Edirne, Turkey, 17 - 20 April 2019, pp.87

2018

2018

TÜRK DEMANS HASTALARINDA FRONTO-TEMPORAL DEMANS İLE İLİŞKİLİ BAŞLICA GENLERDEKİ MUTASYON SIKLIĞI

Güven Z. G. , Lohmann E., Bras J., Gibbs R., Gürvit İ. H. , Bilgiç B. , et al.

Uluslararası Katılımlı 13. Ulusal Tıbbi Genetik Kongresi, Antalya, Turkey, 7 - 11 November 2018, pp.142

2017

2017

GENETIC CHARACTERIZATION OF A TURKISH DEMENTIA COHORT: FOCUS ON TYROBP

Carmona S., Güven Z. G. , Lohmann E., Singleton A., Hardy J., Bras J., et al.

The Alzheimer’s Association International Conference 2017, London, United Kingdom, 15 - 20 July 2017, vol.13, pp.1490-1491

2017

2017

EFFECTS OF VARIOUS GRN VARIANTS ON MRNA AND SERUM PGRN LEVEL

GÜVEN Z. G. , G R., ÜNALTUNA N. , GÜRVİT İ. H. , HANAĞASI H. A. , B J., et al.

3th International Conference on Alzheimer’s and Parkinson’s Diseases, Viyana, Austria, 29 March - 02 April 2017, pp.1674

2016

2016

GRN c.708 + 1_+4del TGAG deletion in a large family diagnosed with fronto-temporal dementia

Babacan Yıldız G., GÜVEN Z. G. , HANAĞASI H. A. , BİLGİÇ B., GÜRVİT İ. H. , ÜNALTUNA N., et al.

10th International Conference on Frontotemporal Dementias, Münih, Germany, 31 August - 02 September 2016, vol.138, pp.323

2016

2016

A novel homozygous DJ1 mutation causes Parkinsonism and ALS in a Turkish family

Hanagasi H. A. , Giri A., Guven G. , Bilgic B., Hauser A. -. , Emre M., et al.

20th International Congress of Parkinson's Disease and Movement Disorders, Berlin, Germany, 19 - 23 June 2016, vol.31 identifier

2015

2015

PSEN1 mutation presenting as posterior cortical atrophy

Gurvit H. , Bilgic B., Hanagasi H. A. , Guven G. , Guerreiro R., Hardy J.

22nd World Congress of Neurology (WCN), Santiago, Chile, 31 October - 05 November 2015, vol.357 identifier

2015

2015

Geç ve erken başlangıçlı Alzheimer hastalığında rol oynayan miRNAların incelenmesi

Güven Z. G. , Lohmann E., Hanağası H. A. , Ünaltuna N.

DETAE Genç Araştırıcılar Toplantısı, İstanbul, Turkey, 19 - 20 January 2015, pp.8

2013

2013

Investigation of SORL1 variants in a Turkish cohort of dementia patients

Güven Z. G. , Guerreiro R., Lohmann E., Bras J., Gibbs R., Singleton A., et al.

European Society of Human Genetics Congress, Paris, France, 8 - 11 June 2013, vol.21, pp.219

2008

2008

Investigation of CYFIP1 and CYFIP2 genes in patients with autosomal recessive non-syndromic mental retardation

Güven Z. G. , Kayserili Karabay H., Üzümcü A., Eriş H., Karaman B. , Başaran S. , et al.

EUROPEAN HUMAN GENETICS CONFERENCE 2008, Barcelona, Spain, 31 May - 03 June 2008, vol.16, pp.271

Supported Projects

2017 - Continues

2017 - Continues

Alzheimer Hastalığı'nda Periferal Mitokondriyal Disfonksiyon

EU Supported Other Project

GÜVEN Z. G.

2017 - 2018

2017 - 2018

Periferik kanda seçilmiş miRNA anlatım düzeylerinin incelenmesi

Project Supported by Higher Education Institutions

ÜNALTUNA N. (Executive), GÜVEN Z. G.

2017 - 2017

2017 - 2017

Alzheimer hastalarında ACSL4 ve CAT genlerinin anlatım düzeylerinin incelenmesi

Project Supported by Higher Education Institutions

ÜNALTUNA N. (Executive), GÜVEN Z. G. , LOHMANN E., ÖZER E.

2017 - 2017

2017 - 2017

Türk demans hastalarında moleküler genetik analizler

Project Supported by Higher Education Institutions

GÜVEN Z. G. (Executive)

2015 - 2017

2015 - 2017

GRN genindeki varyantların etkilerinin araştırılması

Project Supported by Higher Education Institutions

ÜNALTUNA N. (Executive), GÜLEÇ Ç., GÜRVİT İ. H. , GÜVEN Z. G.

Memberships / Tasks in Scientific Organizations

2018 - Continues

2018 - Continues

Tıbbi Genetik Derneği

Member

Scientific Refereeing

April 2019

April 2019

NEUROBIOLOGY OF AGING

SCI Journal

February 2019

February 2019

NEUROBIOLOGY OF AGING

SCI Journal

Awards

April 2017

April 2017

Poster Birincilik Ödülü

7.Ulusal Alzheimer Kongresi



Congress and Symposium Activities

10 April 2021 - 11 April 2021

10 April 2021 - 11 April 2021

6. Uluslararası Tıp ve Sağlık Bilimleri Araştırmaları Kongresi

Attendee

Ankara-Turkey

05 November 2020 - 08 November 2020

05 November 2020 - 08 November 2020

10. Ulusal Alzheimer Sanal Kongresi

Attendee

İstanbul-Turkey

02 May 2019 - 04 May 2019

02 May 2019 - 04 May 2019

9. Ulusal Alzheimer Kongresi

Attendee

Ankara-Turkey

17 April 2019 - 20 April 2019

17 April 2019 - 20 April 2019

13. Balkan Genetics Congress of Human GeneticsSustainable Development

Attendee

Edirne-Turkey

07 November 2018 - 11 November 2018

07 November 2018 - 11 November 2018

13. Ulusal Tıbbi Genetik Kongresi

Attendee

Antalya-Turkey

27 September 2018 - 28 September 2018

27 September 2018 - 28 September 2018

Kişiselleştirilmiş Tıp ve Moleküler Tanı Sempozyumu

Attendee

İstanbul-Turkey

16 June 2018 - 19 June 2018

16 June 2018 - 19 June 2018

European Human Genetics Conference 2018

Attendee

Milan-Italy

20 April 2017 - 23 April 2017

20 April 2017 - 23 April 2017

7. Ulusal Alzheimer Kongresi

Attendee

Konya-Turkey

01 May 2016 - 01 May 2016

01 May 2016 - 01 May 2016

European Human Genetics Conference 2016

Attendee

Barcelona-Spain

07 April 2016 - 08 April 2016

07 April 2016 - 08 April 2016

DETAE Genç Araştırıcı Toplantısı

Attendee

İstanbul-Turkey

06 April 2016 - 07 April 2016

06 April 2016 - 07 April 2016

Geleceğe Yatırım:BİYOBANKA Protokol ve Etik Çalıştayları

Audience

İstanbul-Turkey

01 November 2015 - 01 November 2015

01 November 2015 - 01 November 2015

7. DETAE Günleri

Attendee

İstanbul-Turkey

21 May 2015 - 21 May 2015

21 May 2015 - 21 May 2015

Nadir Görülen Nörolojik Hastalıklar Sempozyumu

Attendee

İstanbul-Turkey

19 January 2015 - 20 January 2015

19 January 2015 - 20 January 2015

DETAE Genç Araştırıcılar Toplantısı

Attendee

İstanbul-Turkey

24 November 2014 - 25 November 2014

24 November 2014 - 25 November 2014

6. DETAE Günleri

Attendee

İstanbul-Turkey

01 March 2014 - 01 March 2014

01 March 2014 - 01 March 2014

4. Ulusal Alzheimer Kongresi

Attendee

İzmir-Turkey

08 June 2013 - 11 June 2013

08 June 2013 - 11 June 2013

European Human Genetics Conference 2013

Attendee

Paris-France

19 December 2012 - 23 December 2012

19 December 2012 - 23 December 2012

10. Ulusal Tıbbi Genetik Kongresi

Attendee

Bursa-Turkey

01 December 2010 - 05 December 2010

01 December 2010 - 05 December 2010

9. Ulusal Tıbbi Genetik Kongresi

Attendee

İstanbul-Turkey

15 October 2009 - 16 October 2009

15 October 2009 - 16 October 2009

1. DETAE Günleri

Attendee

İstanbul-Turkey

08 October 2009 - 10 October 2009

08 October 2009 - 10 October 2009

Endokrin Hastalıklar ve Genetik Sempozyumu

Attendee

Bolu-Turkey

05 May 2009 - 08 May 2009

05 May 2009 - 08 May 2009

III. International Congress of Molecular Medicine

Attendee

İstanbul-Turkey

26 March 2009 - 27 March 2009

26 March 2009 - 27 March 2009

II. Istanbul International Symposium on Public Health GenomicsSustainable Development

Attendee

İstanbul-Turkey

31 May 2008 - 03 June 2008

31 May 2008 - 03 June 2008

European Human Genetics Conference 2008

Attendee

Barcelona-Spain

06 May 2008 - 09 May 2008

06 May 2008 - 09 May 2008

8. Ulusal Tıbbi Genetik Kongresi

Attendee

Çanakkale-Turkey

20 February 2008 - 22 February 2008

20 February 2008 - 22 February 2008

EMBO Young Scientists Forum

Attendee

İstanbul-Turkey

02 November 2007 - 03 November 2007

02 November 2007 - 03 November 2007

Gene Therapy Symposium

Attendee

İstanbul-Turkey

06 September 2007 - 09 September 2007

06 September 2007 - 09 September 2007

10. Ulusal Tıbbi Biyoloji Kongresi

Attendee

Antalya-Turkey

07 July 2007 - 10 July 2007

07 July 2007 - 10 July 2007

6th European Cytogenetics Conference

Attendee

İstanbul-Turkey

26 May 2006 - 27 May 2006

26 May 2006 - 27 May 2006

II. Tıbbi Biyolojik Bilimler Kongresi ve V. Tıbbi Biyolojik Bilimler Öğrenci Sempozyumu

Attendee

İstanbul-Turkey

17 May 2006 - 20 May 2006

17 May 2006 - 20 May 2006

7. Ulusal Tıbbi Genetik Kongresi, Ulusal Prenatal Tanı ve Tıbbi Genetik Kongresi

Attendee

Kayseri-Turkey

Invited Talks

December 2018

December 2018

Nörodejeneratif Hastalıkların Genetiği

Seminar

İTF Sinirbilim Kulübü Nörogenetik Sempozyumu-Turkey

Scholarships

2016 - 2016

2016 - 2016

European Human Genetics Conference 2016 Fellowship Award

Other International Organizations

Citations

Total Citations (WOS): 430

h-index (WOS): 9