Education
1994 - 2001
1994 - 2001Doctorate
Istanbul University, Institute of Graduate Studies In Sciences, Biyoloji Anabilim Dalı-Moleküler Biyoloji Genetik Rogramı, Turkey
1990 - 1992
1990 - 1992Postgraduate
Istanbul University, İ.Ü.Fen Bilimleri Enstitüsü, Biyoloji Anablim Dalı-Moleküler Biyoloji Programı, Turkey
1978 - 1982
1978 - 1982Undergraduate
Istanbul University, Faculty of Science, Depertment of Biology, Turkey
Dissertations
2001
2001Doctorate
Schizosaccharomyces pombe'de İnozin Monofosfat Dehidrogenaz (gua1) Geninin Klonlanması ve Yapısal Analizi
Istanbul University, Biyoloji Bölümü, Moleküler Biyoloji Ve Genetik
1992
1992Postgraduate
Schizosaccharomyces pombe'de Arginin Biyosentezi ile ilişkili Bazı Genlerin Haritalanması
Istanbul University, Biyoloji Bölümü, Moleküler Biyoloji Ve Genetik
Certificates, Courses and Trainings
2014
2014Türk Müziği sertifikalı eğitim kursu
Other
İstanbul Üniversitesi
2012
2012Ölçme Ve Değerlendirme
Education Management and Planning
İstanbul Üniversitesi Hasan Ali Yücel Eğitim Fakültesi
2003
2003Pedagojik Formasyon Sertifikası
Education Management and Planning
İstanbul Üniversitesi Hasan Ali Yücel Eğitim Fakültesi
Research Areas
Natural Sciences
Academic Positions
2018 - Present
2018 - PresentAssistant Professor
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
2007 - 2018
2007 - 2018Assistant Professor
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
Managerial Experience
2013 - 2018
2013 - 2018Deputy Head of Department
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
Non Academic Experience
1985 - 2007
1985 - 2007Biyolog
İstanbul.Üniversitesi Fen Fakültesi Biyoloji Bölümü, Biyolog
Supervised Theses
in Progress
in ProgressPostgraduate
Hücre iskeleti proteini Rlc1 ile ER stresi arasındaki ilişkinin Schizosaccharomyces pombe'de araştırılması
Karaer Uzuner S. (Advisor)
R.sakallı(Student)
2021
2021Doctorate
Schizosaccharomyces pombe'nin Alzheimer hastalığı için model organizma olarak geliştirilmesi
Karaer Uzuner S. (Advisor)
M.YILMAZER(Student)
2020
2020Postgraduate
the effect of tunıcamycın on wortmannın resıstant Shizosacchoromyces pombe mutants
Karaer Uzuner S. (Advisor)
m.yemenici(Student)
2018
2018Postgraduate
Schizosaccharomyces pombe'de Glukoz Metabolizmasının Biyoinformatik ve Transkriptomik Analizi
Karaer Uzuner S. (Advisor)
M.Tan(Student)
2016
2016Postgraduate
Ortam koşullarının Schizosaccharomyces pombe'de Rec12 Gen Anlatımı ve Homolog Rekombinasyon Üzerine Etkisi
Karaer Uzuner S. (Advisor)
D.Yılmaz(Student)
2014
2014Postgraduate
Schizosaccharomyces pombe'de gua1 geninin Knock-out tekniği ile delesyona uğratılması
Karaer Uzuner S. (Advisor)
M.Yılmazer(Student)
Articles
2025
20251. Tau protein expression and phosphorylation in a glucose-repressed yeast model: Insights into the cancer-alzheimer’s disease link
YILMAZER M., Uzuner S. K.
International Journal of Medical Biochemistry
, vol.8, no.4, pp.272-281, 2025 (Scopus)
2025
20252. Glucose starvation induces tau phosphorylation leading to cellular stress response in fission yeast
YILMAZER M., Şengelen A., Aksüt Y., PALABIYIK B., ÖNAY UÇAR E., KARAER UZUNER S.
Archives of Microbiology
, vol.207, no.7, 2025 (SCI-Expanded, Scopus)
2024
20243. Effects of ScRgt1-Like DNA-binding transcription factor SpRgt1 (SPCC320.03) on Hexose transporters gene expression in Schizosaccharomyces pombe
Ibisoglu M. S., Tan M., YILMAZER M., Yilmaz S., Uzuner S. K., Topal-Sarikaya A., et al.
Archives of Microbiology
, vol.206, no.4, 2024 (SCI-Expanded)
2024
20244. Effects of Glucose on the Cellular Respiration in Fission Yeast Expressing Human GSK3β Gene
Yılmazer M., Karaer Uzuner S.
TRAKYA UNIVERSITY JOURNAL OF NATURAL SCIENCES
, vol.25, no.1, pp.1-10, 2024 (ESCI)
2022
20225. Involvement of Sec71 and Ubp2 in tunicamycin-induced ER stress response in the fission yeast.
Yemenici M., Kartal Sural B., Karaer Uzuner S., Palabıyık B.
Molecular biology reports
, vol.49, no.6, pp.4719-4726, 2022 (SCI-Expanded)
2020
20206. HETEROLOGOUS EXPRESSION OF TAU PROTEIN IN FISSION YEAST AS A DISEASE MODEL
Yilmazer M., Uzuner S. K.
FRESENIUS ENVIRONMENTAL BULLETIN
, vol.29, no.10, pp.9218-9225, 2020 (SCI-Expanded)
2019
20197. A Genome-Wide Screen for Wortmannin-Resistant Mutants in Schizosaccharomyces pombe: The Phosphorylation-Impaired Mutants Are Resistant to Signaling Defect
Yilmazer M., Kartal B., Tarhan C., Ozarabaci I., Akcaalan S., Ozkan E., et al.
DNA AND CELL BIOLOGY
, vol.38, pp.1427-1436, 2019 (SCI-Expanded)
2018
20188. CHEMICALLY INDUCED OXIDATIVE STRESS DECREASES HOMOLOGOUS RECOMBINATION RATE AND REC12 GENE EXPRESSION IN THE FISSION YEAST
Yilmaz D., Yilmazer M., Tumkaya T., Karaer Uzuner S.
FRESENIUS ENVIRONMENTAL BULLETIN
, vol.27, no.7, pp.4995-5000, 2018 (SCI-Expanded)
2017
20179. Generation of gua1 deletion using polymerase chain reaction (PCR)-mediated gene disruption method in fission yeast, Schizosaccharomyces pombe
Yılmazer M., Palabıyık B., Topal Sarıkaya A., Karaer Uzuner S.
AFRICAN JOURNAL OF BIOTECHNOLOGY , no.16, pp.1501-1506, 2017 (Peer-Reviewed Journal)
2016
201610. Role of glucose repression in the oxidative stress response of Schizosaccharomyces pombe: analysis of transcript levels of fbp1, hxk2, sod1 and ctt1 genes in sty1, atf1 and pap1 knock-out mutants
Palabiyik B., Jafari Ghods F., Karaer Uzuner S.
TURKISH JOURNAL OF BIOLOGY
, vol.40, no.4, pp.815-825, 2016 (SCI-Expanded)
2015
201511. SILENCING OF G-PROTEIN alpha-SUBUNIT IN BARLEY (Hordeum vulgare L.) BY VIGS AND ITS EFFECT ON THE PLANT GROWTH
SHAHID M. Q., Ucarli C., Karlik E., Uzuner S., Gurel F.
TURKISH JOURNAL OF FIELD CROPS
, vol.20, no.2, pp.259-264, 2015 (SCI-Expanded)
2010
201012. Intracellular scavenging actiivity of Trolox (6-hydroxy-2,5,7,8-tetramethylchromane-2-caboxylic acid9 in the fission yeast, Schizosacchoaromyces pombe
Hamad İ., Arda N., Pekmez M., Karaer Uzuner S., Temizkan G.
journal of Natural Science,Biology and AMERICAN JOURNAL OF MEDICINE , vol.1, pp.16-21, 2010 (Peer-Reviewed Journal)
2010
201013. Expression of Human A4V Mutant Cu,Zn Superoxide Dismutase in Schizosaccharomyces pombe: Investigations of its Toxic Properties
Karaer S., Tarhan C., Pekmez M., HAMAD I., Arda N., Sarikaya A. T.
BIOCHEMICAL GENETICS
, vol.48, no.1-2, pp.113-124, 2010 (SCI-Expanded)
2008
200814. Expression of human cytochrome p450 3A4 gene in Schizosaccharomyces pombe
Palabiyik B., Karaer S., Arda N., Toker S., Temizkan G., Kelly S., et al.
BIOLOGIA
, vol.63, no.3, pp.450-454, 2008 (SCI-Expanded)
2007
200715. The effect of superoxide dismutase deficiency on zinc toxicity in Schizosaccharomyces pombe
Tarhan C., Pekmez M., Karaer S., Arda N., Sarikaya A. T.
JOURNAL OF BASIC MICROBIOLOGY
, vol.47, no.6, pp.506-512, 2007 (SCI-Expanded)
2006
200616. The 3 ' terminal sequence of the inosine monophosphate dehydrogenase gene encodes an active domain in the yeast Schizosaccharomyces pombe
Karaer S., Sarikaya A. T., Arda N., Temizkan G.
GENETICS AND MOLECULAR BIOLOGY
, vol.29, no.3, pp.551-557, 2006 (SCI-Expanded)
2001
200117. Regulation of the expression of ade2 gene in fission yeast.
Temizkan G., Gunel T., Kig C., Karaer S.
YEAST
, vol.18, 2001 (SCI-Expanded)
2001
200118. DISRUPTION of gene encoding 16 kDa subunit of Schizosaccharomyces pombe vacuolar H+ATPase.
Akman G., Sarykaya A., Karaer S., Temizkan G.
YEAST
, vol.18, 2001 (SCI-Expanded)
2001
200119. Schizosaccharomyces pombe partial gua1 gene for IMP dehydrogenase.
Karaer S., Topal-Sarykaya A., Temizkan G.
YEAST
, vol.18, 2001 (SCI-Expanded)
Papers Presented at Peer-Reviewed Scientific Conferences
2024
20241. THE ROLE OF VITAMIN B6 IN REDUCING TAU PROTEIN-INDUCED ENDOPLASMIC RETICULUM STRESS IN SCHIZOSACCHAROMYCES POMBE
YILMAZER M., KARAER UZUNER S., PALABIYIK B.
13th INTERNATIONAL MARMARA SCIENCE AND SOCIAL SCIENCES CONGRESS, Kocaeli, Turkey, 29 - 30 November 2024, pp.33, (Summary Text)
2024
20242. Effects of Metformin on Human GSK3β Gene Expression in Fission Yeast
Yılmazer M., Gökçay M., Canbazoğlu S., Akkülah C., Karaer Uzuner S.
ICANAS 2024 7th International Conference on Advances in Natural and Applied Sciences, Antalya, Turkey, 17 - 20 April 2024, pp.123-124, (Summary Text)
2023
20233. Water-Based Propolis Prevents Protein Oxidation in Fission Yeast Grown At High Glucose Concentration
Kocameşe B., Aksüt Y., Karaer Uzuner S., Yılmazer M., Arda E. Ş. N.
3. International Propolis Conference, İstanbul, Turkey, 9 - 11 November 2023, pp.66, (Summary Text)
2023
20234. Heterologous Expression of Human Gsk3Β Gene in Schizosaccharomyces pombe
YILMAZER M., KARAER UZUNER S.
V. International Conference on Agricultural, Biological and Life Science, 18 September 2023, (Summary Text)
2023
20235. Hücre İskeletinde Rol Oynayan rlc1 Geninin pSGP572 Plazmidine Klonlanması
Sakallı R., YILMAZER M., KARAER UZUNER S.
25. Ulusal Biyoloji Kongresi, 13 July 2023, (Summary Text)
2022
20226. Effects of Heterologous Tau Protein in Schizosaccharomyces pombe
YILMAZER M., KARAER UZUNER S.
9. International Marmara Sciences Congress, Kocaeli, Turkey, 09 December 2022, pp.54, (Summary Text)
2019
20197. A genome-wide screen for wortmann in and hydrogen peroxide resistant mutants in Schizosaccharomyces pombe
Yılmazer M., Kartal B., Tarhan Ç., Özarabacı İ., Akçaalan S., Özkan E., et al.
7th International Congress of the Molecular Biology Association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, vol.1, no.1, pp.163, (Summary Text)
2015
20158. Schizosaccharomyces pombe’de Gua1 Geninin Knock-Out Tekniği ile Delesyona Uğratılması
YILMAZER M., KARAER UZUNER S., PALABIYIK B., Topal Sarıkaya A.
18. Ulusal Biyoteknoloji Kongresi, Konya, Turkey, 18 - 19 December 2015, pp.258, (Summary Text)
2015
20159. "Allelic diversity in Hodeum spontaneum at the Dhn3 locus: a major dehydration stress-inducible gene in barley
Çaputlu s., UÇARLI C., Yörük E., KARAER UZUNER S., GÜREL A. F.
Botany 2015, Edmonton, Canada, 25 - 29 July 2015, pp.367, (Full Text)
2013
201310. The effects of Astragalus chrysochlorus crude extract on cancer model of Schizosaccharomyces pombe cells
Karaer Uzuner S., Tarhan Ç., Arı Ş.
Pombe 2013, 7th International Fission Yeast Meeting, London, United Kingdom, 1 - 04 June 2013, pp.188, (Full Text)
2013
201311. Hydrocortisone effect on Schizosaccharomyces pombe's rad17+ gene expression.
TARHAN Ç., ŞATIR T. M., YILMAZER M., KARAER UZUNER S.
EMBO Conference Pombe 2013 7th International Fission Yeast Meeting, Londra, United Kingdom, 1 - 04 May 2013, no.185, pp.323, (Full Text)
2007
200712. Fission yeast as a model for ALS disease
Karaer S., Tarhan C., Hamad I., Pekmez M., Arda N., Sarikaya A. T.
13th European Congress on Biotechnology (ECB 13), Barcelona, Spain, 16 - 19 September 2007, vol.131, (Summary Text)
2006
200613. Protective effects of Trolox in the yeast Schizosaccharomyces pombe
Hamad I., Arda N., Pekmez M., Karaer S., Temizkan G.
31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Turkey, 24 - 29 June 2006, vol.273, pp.166, (Summary Text)
1995
199514. RAPD Markırları ile DNA Parmakizi Çıkarılması
Albayrak (Çobanoğlu) G., Karaer Uzuner S., Topohan G., Palabıyık (Gemici) B., Can Ö., Gözükırmızı N.
Biyoteknoloji ve Bitki Islahı, Kocaeli, Turkey, 17 - 19 April 1995, pp.157-162, (Full Text)
Books
2018
20181. Shizosaccharomyces pombe inozin Monofosfat Dehidrogenaz (gua1) Geninin Klonlanması
KARAER UZUNER S.
in: Temel ve İleri Moleküler Biyoloji Yöntemleri, Temizkan G,Arda N., Editor, Nobel Tıp Kitapevi Yayınları, İstanbul, pp.281-291, 2018
2002
20022. Bakterilerden Genom ve Plazmit DNA’sı İzolasyonu
Arı Ş., Karaer Uzuner S.
in: Genetik Mühendisliğinde Kullanılan Yöntemler Uygulamalı Yaz Eğitimi Kitabı, Güler Temizkan, Editor, BİYOGEM, İstanbul, pp.19-27, 2002
Other Publications
Funded Projects
2019 - 2020
2019 - 2020"Wortmannin'e dirençli Shizosaccharomyces pombe mutantlarına Tunikamisin'in Etkisi
Project Supported by Higher Education Institutions , BAP MSc
KARAER UZUNER S. (Executive), YEMENİCİ M.
2016 - 2017
2016 - 2017GIDALARDA TATLANDIRICI OLARAK KULLANILAN FRUKTOZ ŞURUBUNUN HÜCRE YAŞLANMASI ÜZERİNE ETKİLERİ
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive), ÇOBAN F., TARHAN Ç., ÖZDEMİR E.
2015 - 2017
2015 - 2017
İnsan hastalıklarının moleküler mekanizmalarının araştırılmasında Schizosaccharomyces pombe'nin model organizma olarak kullanılmasının optimizasyonu
Project Supported by Higher Education Institutions , BAP Research Project
PALABIYIK B. (Executive), YILMAZER M., TARHAN Ç., KARAER UZUNER S., ARICAN E., ÖZCAN F. G., et al.
2016 - 2016
2016 - 2016Schizosaccharomyces pombe'de Branched Chain Amico Acid Aminotransferase (Eca39) Geninin Yaşlanma Üzerindeki Etkisinin Araştırılması
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive), ISENI T., YANIK A., TARHAN Ç.
2013 - 2016
2013 - 2016MOLEKÜLER BİYOTEKNOLOJİ LABORATUVARININ KURULMASI
Project Supported by Higher Education Institutions , BAP Guided
ARDA E. Ş. N. (Executive), UÇARLI C., ARICAN E., ALBAYRAK G., GÜREL A. F., ARI Ş., et al.
2013 - 2015
2013 - 2015SCHIZOSACCHAROMYCES POMBE'DE GUA1 GENİNİN KNOCK-OUT TEKNİĞİ İLE DELESYONA UĞRATILMASI
Project Supported by Higher Education Institutions , BAP MSc
KARAER UZUNER S. (Executive), YILMAZER M.
2013 - 2013
2013 - 2013Hydrocortisone effect on Schizosaccharomyces pombe's rad17+ Gene Expression
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive)
2012 - 2013
2012 - 2013Schizosaccharomyces pombe'de gua1 geninin tam delesyona uğratılarak mutant elde edilmesi
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive)
2011 - 2011
2011 - 2011IMPDH enzimi anlatımı artırılmış S.pombe hücrelerinde çeşitli oksidatif stres uygulamaları
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive)
2009 - 2009
2009 - 2009INVESTIGATION OF THE EFFECTS OF MYCOPHENOLIC ACID, MIZORIBIN and RIBAVIRIN ON SCHIZOSACCHAROMYCES POMBE CELLS
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive)
2007 - 2008
2007 - 2008Schizosaccharomyces pombe'de İnozin Monofosfat Dehidrogenaz enziminin aktif domaini kodlayan gen bölgesi
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive)
1996 - 1998
1996 - 1998Mayada Heterolog Gen Ekspresyonu
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
(Project Abstract)
Topal Sarıkaya A.(Executive), Palabıyık B., Karaer Uzuner S.
Peer Reviews in Scientific Publications
October 2016
October 2016Turkish Journal Of Biology
SCI Journal
May 2011
May 2011TÜBAV Bilim Dergisi
National Scientific Refreed Journal
Scientific Project Refereeing
April 2013
April 2013TUBITAK Project
Congress and Symposium Activities
01 December 2017 - 01 December 2017
01 December 2017 - 01 December 2017VI.İnternational congress on Molecular Biology and Biotechnology
Attendee
Afyon-Turkey
01 December 2015 - 01 December 2015
01 December 2015 - 01 December 201518.ulusal Biyoteknoloji Kongresi
Attendee
Konya-Turkey
01 June 2013 - 01 June 2013
01 June 2013 - 01 June 2013Araştırma günü etkinliği
Attendee
istanbul-Turkey
01 June 2013 - 01 June 2013
01 June 2013 - 01 June 20137th International Fission Yeast Meeting
Attendee
Londra-United Kingdom
01 June 2012 - 01 June 2012
01 June 2012 - 01 June 2012Yaşam bilimlerinde multidisipliner AR-GE ve İnovasyon sempozyumu
Attendee
istanbul-Turkey
01 September 2007 - 01 September 2007
01 September 2007 - 01 September 2007Journal of Biotechnology 13th European Congress on Biotechnology
Attendee
-Spain
01 July 2007 - 01 July 2007
01 July 2007 - 01 July 200713 Th European Congress on Biotechnology Journal of Biotechnology
Attendee
-Spain
01 August 2005 - 01 August 2005
01 August 2005 - 01 August 2005XXIInd Internatianal Conference on Yeast Genetics and Molecular Biology
Attendee
-Slovakia
01 August 2001 - 01 August 2001
01 August 2001 - 01 August 2001XX. International Conferance on Yeast Genetics and Molecular Biology
Attendee
-Czech Republic
01 August 2001 - 01 August 2001
01 August 2001 - 01 August 2001XXth International Conference on Yeast Genetics and Molecular Biology
Attendee
-Czech Republic
01 August 2001 - 01 August 2001
01 August 2001 - 01 August 2001XXth International Conference on Yeast Genetics and Molecular Biology
Attendee
-Czech Republic
01 September 2000 - 01 September 2000
01 September 2000 - 01 September 2000The World Congress on Biotechnology
Attendee
-Germany
01 September 2000 - 01 September 2000
01 September 2000 - 01 September 2000Tenth International Symposium on Yeasts, 2
Attendee
-Netherlands
01 September 1999 - 01 September 1999
01 September 1999 - 01 September 1999The First İnternational Fission Yeast Meeting
Attendee
-United Kingdom
Scholarships
1995 - 1998
1995 - 1998