Rapid, ultrasensitive, highly selective detection of toxic Hg(II) ions in seabass, swordfish and water samples

Erdemir E., Suna G., Gunduz S., Şahin M., Eglence-Bakir S., Karakus E.

FOOD CHEMISTRY, vol.371, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 371
  • Publication Date: 2022
  • Doi Number: 10.1016/j.foodchem.2021.131309
  • Journal Name: FOOD CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, EMBASE, Food Science & Technology Abstracts, MEDLINE, Metadex, Veterinary Science Database, Civil Engineering Abstracts
  • Keywords: Triphenylamine, Fluorescent probe, Mercury(II) ions detection, Thiosemicarbazide, Water and seafood analysis, FLUORESCENT-PROBE, MERCURY, METHYLMERCURY, EXPOSURE, HG2+, RISK, GOLD, FISH
  • Istanbul University Affiliated: Yes


A novel fluorescent probe bearing triphenylamine, thiophene and thiosemicarbazide (TPA-TSC) was developed, and its distinct features were investigated. TPA-TSC demonstrated excellent selectivity towards Hg2+ ions, with a limit of detection (0.14 nM) among the lowest reported to date. It also exhibited a turn-off response by forming stable complex for a brief period (<30 s). Job plot analysis and high-resolution mass spectrometry (HRMS) revealed that TPA-TSC bound to Hg2+ with a 2:1 stoichiometry in an aqueous environment, remarkably the probe successfully detected Hg2+ ions in seabass, swordfish and different samples of water. In all, TPA-TSC offers a promising method for accurately determining the quality of seafood and water samples polluted with Hg2+.