Protective effects of olive oil phenolics and gallic acid on hydrogen peroxide-induced apoptosis

Erol-Dayi O., Arda N., Erdem G.

EUROPEAN JOURNAL OF NUTRITION, cilt.51, sa.8, ss.955-960, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 8
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s00394-011-0273-5
  • Dergi Adı: EUROPEAN JOURNAL OF NUTRITION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.955-960
  • Anahtar Kelimeler: Anti-apoptotic effect, Gallic acid, Olive, Oxidative stress, Phenolic compounds, OXIDATIVE DNA-DAMAGE, ANTIOXIDANT, CELLS, HYDROXYTYROSOL, PROLIFERATION, EXTRACTS, NUCLEAR, TYROSOL, STRESS, HL60
  • İstanbul Üniversitesi Adresli: Evet

Özet

Olive oil contains several phenolic compounds possessing antioxidant activity. The aim of this study was to investigate the protective effects of olive oil phenolic extract (OOPE) and one of its constituents, gallic acid (GA) against H2O2-induced oxidative stress and apoptotic cell death in HeLa cells, a model for human epithelial cells.