Education Information
2009 - 2014
2009 - 2014Doctorate
Istanbul University, Deneysel Tıp Araştırma Enstitüsü, Genetik Anabilim Dalı, Turkey
2006 - 2008
2006 - 2008Postgraduate
Wake Forest University, Graduate School Of Arts And Sciences, Molecular Genetics And Genomics Program, United States Of America
2002 - 2006
2002 - 2006Undergraduate
Sabanci University, Faculty Of Engıneerıng, Biyoloji Bilimleri Ve Biyomühendislik, Turkey
Dissertations
2014
2014Doctorate
Ailesel Geçiş Gösteren İdiyopatik Epilepsilerin Genetik Altyapısının Aydınlatılması
Istanbul University, Deneysel Tıp Araştırma Enstitüsü, Genetik
2008
2008Postgraduate
Identifying genes in pancreatic beta-cell function using a novel high-throughput cell-based screening assay
Wake Forest University, Tıp Fakültesi, Moleküler Genetik Ve Genomik
Foreign Languages
C1 Advanced
C1 AdvancedEnglish
B1 Intermediate
B1 IntermediateGerman
Certificates, Courses and Trainings
2013
2013Next Generation Sequencing (NGS) Data Analysis Course
Education Management and Planning
Erasmus Üniversitesi
2013
2013Genetic Association Course
Education Management and Planning
Max Delbrück Center for Molecular Medicine
2011
2011Molecular Diagnosis of Congenital Erythrocytosis theory, practice
Education Management and Planning
COST Action BM0902
2010
2010EMBO|EMBL Symposium: The Non-coding Genome
Other
EMBL
2010
2010From Gene Mutations to Animal Models of Epilepsy and Back
Education Management and Planning
Institut de Neurobiologie de la Méditerranée (INMED)
Research Areas
Life Sciences
Molecular Biology and Genetics
Genetic Disorders
Genetic Engineering
Natural Sciences
Academic Titles / Tasks
2020 - Continues
2020 - ContinuesAssociate Professor
Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics
2016 - 2021
2016 - 2021Assistant Professor
Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics
2010 - 2016
2010 - 2016Research Assistant
Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics
2006 - 2008
2006 - 2008Expert
Wake Forest University, Tıp Fakültesi, Moleküler Genetik Ve Genomik
Advising Theses
2019
2019Postgraduate
Valproik AsitIe İndüklenen PANC-1 Hücrelerinde Wnt Sinyal Yolağının İncelenmesi
TUNCER KILINÇ F. N.
F.Yeliz(Student)
2018
2018Postgraduate
Farklılaşmş PANC-1 Hücrelerinde INSIG1 Geninin İncelenmesi
TUNCER KILINÇ F. N.
M.Sema(Student)
Published journal articles indexed by SCI, SSCI, and AHCI
2024
2024The effects of enoxaparin treatment in a xenograft mouse model of oral squamous cell carcinoma: A pilot study.
Ekici Y., SOLUK TEKKEŞİN M., KÜÇÜKSEZER U. C., Celebioglu H. B., Tuncer E. B., Bedeloglu E., et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
, vol.53, no.7, pp.491-494, 2024 (SCI-Expanded)
2024
2024Whole Exome Sequencing Revealed Paternal Inheritance of Obesity-related Genetic Variants in a Family with an Exclusively Breastfed Infant.
Olgun Celebioglu H. B., Ozturk A. P., Poyrazoglu Ş., Tuncer F. N.
Journal of clinical research in pediatric endocrinology
, 2024 (SCI-Expanded)
2024
2024Whole exome sequencing reveals novel candidate variants for endometriosis utilizing multiple affected members in a single family
Kına B. G., Topbas Selcuki N. F., Bahat P. Y., Usta A. T., Aydın S., Rahmioglu N., et al.
Molecular Genetics and Genomic Medicine
, vol.12, no.1, 2024 (SCI-Expanded)
2022
2022Exome sequencing reveals novel candidate variants for endometriosis and endometrial serous adenocarcinoma in a single family having multiple affected members
Kina B. G., Selcuki N. F. T., Bahat P. Y., Usta T., Tuncer F. N., Oral E.
HUMAN REPRODUCTION
, vol.37, 2022 (SCI-Expanded)
2022
2022Investigation of Wnt signaling pathway components in VPA induced PANC 1 cells
Ekici Y., Yilmaz A., Kucuksezer U., Gazioglu S. B., Yamalioglu Z. D., Gurol A. O., et al.
EUROPEAN JOURNAL OF HUMAN GENETICS
, vol.30, no.SUPPL 1, pp.420-421, 2022 (SCI-Expanded)
2021
2021Combined evaluation of proliferation and apoptosis to calculate IC<sub>50</sub> of VPA-induced PANC-1 cells and assessing its effect on the Wnt signaling pathway
Ekici Y., Yilmaz A., Kucuksezer U. C., Gazioglu S., Yamalioglu Z. D., Gurol A. O., et al.
MEDICAL ONCOLOGY
, vol.38, no.9, 2021 (SCI-Expanded)
2019
2019Biallelic loss of EEF1D function links heat shock response pathway to autosomal recessive intellectual disability
Iseri S. A., YÜCESAN E., Tuncer F. N., Calik M., Kesim Y., Uzun G. A., et al.
JOURNAL OF HUMAN GENETICS
, vol.64, no.5, pp.421-426, 2019 (SCI-Expanded)
2019
2019Identification of INSIG1 gene variants in PANC-1 cell line
Ayaz M. S., Tuncer Kılınç F. N.
INTERCIENCIA , no.44, pp.114-123, 2019 (SCI-Expanded)
2019
2019Three Novel MEN1 Variants in AIP-Negative Familial Isolated Pituitary Adenoma Patients.
Yarman S., Tuncer F. N., Serbest E.
Pathobiology : journal of immunopathology, molecular and cellular biology
, vol.86, pp.128-134, 2019 (SCI-Expanded)
2018
2018A novel homozygous GALC variant has been associated with Krabbe disease in a consanguineous family
Tuncer F. N., Iseri S. A., Yapici Z., Demir M., Karaca M., Calik M.
NEUROLOGICAL SCIENCES
, vol.39, no.12, pp.2123-2128, 2018 (SCI-Expanded)
2018
2018Screening of AIP Gene Variations in a Cohort of Turkish Patients with Young-Onset Sporadic Hormone-Secreting Pituitary Adenomas
Tuncer F. N., Dogansen S. C., Serbest E., Tanrikulu S., Ekici Y., Bilgic B., et al.
GENETIC TESTING AND MOLECULAR BIOMARKERS
, vol.22, no.12, pp.702-708, 2018 (SCI-Expanded)
2016
2016A novel mutation in PCDH19 enabled genetic diagnosis as Epilepsy and Mental Retardation Limited to Females
TUNCER KILINÇ F. N., UĞUR İŞERİ S. A., Kara B., Maraş Genç H., Uyur Yalçın E., ÖZBEK U.
EUROPEAN JOURNAL OF HUMAN GENETICS , vol.24, pp.192, 2016 (SCI-Expanded)
2016
2016Screening LGI1 in a cohort of 26 lateral temporal lobe epilepsy patients with auditory aura from Turkey detects a novel de novo mutation
Kesim Y. F., Uzun G. A., Yucesan E., Tuncer F. N., Ozdemir O., Bebek N., et al.
EPILEPSY RESEARCH
, vol.120, pp.73-78, 2016 (SCI-Expanded)
2015
2015A clinical variant in SCN1A inherited from a mosaic father cosegregates with a novel variant to cause Dravet syndrome in a consanguineous family
Tuncer F. N., Görmez Z., Calik M., Uzun G. A., SAGIROGLU M. S., YUCETURK B., et al.
EPILEPSY RESEARCH
, vol.113, pp.5-10, 2015 (SCI-Expanded)
2014
2014A CASE OF L-2 HYDROXYGLUTARIC ACIDURIA PRESENTING AS FEBRILE SEIZURE
Calik M., Tuncer F. N., Sarikaya S., Karakas O., Cece H., İŞCAN A.
GENETIC COUNSELING
, vol.25, no.4, pp.363-367, 2014 (SCI-Expanded)
2013
2013Identifying SNP targeted pathways in partial epilepsies with genome-wide association study data
Bakir-Gungor B., Baykan B., Iseri S. U., Tuncer F. N., Sezerman O. U.
EPILEPSY RESEARCH
, vol.105, pp.92-102, 2013 (SCI-Expanded)
2013
2013The Role of MDR1 C3435T Gene Polymorphism on Gingival Hyperplasia in Turkish Renal Transplant Patients Treated With Cyclosporine in the Absence of Calcium Channel Blockers
Kazancioglu H. O., Ak G., Turkmen A., Ozbek U., Tuncer F. N., Karabulut A. E.
TRANSPLANTATION PROCEEDINGS
, vol.45, no.6, pp.2233-2237, 2013 (SCI-Expanded)
Articles Published in Other Journals
2022
2022Sporadic Adrenocorticotropic Hormone-Secreting Lung Carcinoids: Outcomes of Long-Term Clinical Follow-Up at a Single Center
Yarman S., Serbest E., Selcukbiricik O. S., Tuncer F. N.
TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
, vol.26, no.3, pp.109-114, 2022 (ESCI)
2022
2022Sporadic Adrenocorticotropic Hormone-Secreting Lung Carcinoids: Outcomes of Long-Term Clinical Follow-Up at a Single Center.
Tuncer Kılınç F. N., Soyluk Selçukbiricik Ö., Serbest E., Yarman E. S.
TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
, vol.26, no.3, pp.109-114, 2022 (ESCI)
2021
2021HEK293T hücrelerinde valproik asidin apoptoz ve proliferasyon üzerine etkilerinin araştırılması
ÇELEBİOĞLU H. B., KÜÇÜKSEZER U. C., TUNCER KILINÇ F. N.
Acta Medica , vol.52, no.3, pp.316-317, 2021 (Peer-Reviewed Journal)
2019
2019OSC-19 hücre hattı kullanımı ile ksenograft oral yassı hücreli karsinoma fare modelinin geliştirilmesi
TUNCER KILINÇ F. N., Akça B., Ekici Y., Bedeloğlu E., KÜÇÜKSEZER U. C.
7TEPE KLİNİK , vol.15, no.1, pp.92-96, 2019 (Peer-Reviewed Journal)
2018
2018Tinzaparin Tedavisinin Oral Yassı Hu¨creli Karsinoma C¸ıplak Fare Modelinde BAX ve CCNB1 Gen Anlatımları U¨zerindeki Etkisi
TUNCER KILINÇ F. N., Ekici Y., Akça B.
TURKISH JOURNAL OF IMMUNOLOGY , vol.6, no.3, pp.131-135, 2018 (Scopus)
2017
2017ADACIK BENZERİ HÜCRE KÜMELEŞMESİNDE GEN ANLATIM DEĞİŞİMLERİ
PODA M., HASANOĞULLARI B. G., Ekici F. Y., TUNCER F. N.
Deneysel Tıp Dergisi , vol.7, no.13, pp.87-92, 2017 (Peer-Reviewed Journal)
2017
2017SPORADİK MEDU¨LLER TİROİD KANSERLİ BİR HASTADA NADİR GO¨RU¨LEN RET PROTO-ONKOGEN MUTASYONU: D631Y
TUNCER F. N., TÜTÜNCÜ Y., YARMAN E. S.
Deneysel Tıp Dergisi
, vol.7, no.13, pp.101-107, 2017 (Peer-Reviewed Journal)
2015
2015Tüm Genom SNP Genotipleme ile Trizomi ve Ebeveyn Etkisinin Tespiti
Kesim F. Y., TUNCER KILINÇ F. N., YUCESAN E., OZDEMIR O., CALIK M., ÖZBEK U., et al.
Deneysel Tıp Degisi , vol.3, no.7, pp.22-27, 2015 (Peer-Reviewed Journal)
2014
2014Tüm Genom SNP Genotipleme ile Trizomi ve Ebeveyn Etkisinin Tespiti
Kesim F. Y., TUNCER KILINÇ F. N., YUCESAN E., OZDEMIR O., CALIK M., ÖZBEK U., et al.
Deneysel Tıp Dergisi , vol.3, no.7, pp.22-27, 2014 (Peer-Reviewed Journal)
Refereed Congress / Symposium Publications in Proceedings
2024
2024Whole Exome Sequencing Reveals Risk-Conferring Variants in a Family Having Early-Onset Obese Children
Çelebioğlu H. B., Tuncer Kılınç F. N.
57th European Society of Human Genetics (ESHG) Conference, Berlin, Germany, 1 - 04 June 2024, pp.1
2023
2023Identification of obesity-related genetic variants in a family with an exclusively breastfed obese infant
Çelebioğlu H. B., Ozturk A. P., Poyrazoğlu Ş., Tuncer Kılınç F. N.
56th Annual Conference of the European-Society-of-Human-Genetics (ESHG), Glasgow, England, 10 - 13 June 2023, pp.162
2023
2023Genetic Analyses Of 20 Turkish FIPA Families Utilizing Whole Exome Sequencing: Preliminary Results Of A Multicenter Collaborative Study
Ertörer M. E., Tuncer Kılınç F. N., Çiftçi S., Tanrıkulu S., Soyluk Selçukbiricik Ö., Topaloğlu Ö., et al.
25 th European Congress of Endocrinology - ECE 2023, İstanbul, Turkey, 13 - 16 May 2023, pp.1-3
2021
2021HEK293T hücrelerinde valproik asidin apoptoz ve proliferasyon üzerine etkilerinin araştırılması
Olgun Çelebioğlu H. B., Ekici Y., Yılmaz A., Küçüksezer U. C., Tuncer Kılınç F. N.
Uluslararası Katılımlı 17. Tıbbi Biyoloji ve Genetik Kongresi, İstanbul, Turkey, 28 - 31 October 2021, pp.316-317
2021
2021Tinzaparin ve enoksaparin tedavisinin apoptoz ve hücre döngüsü genleri üzerindeki etkisini değerlendirmek için oral skuamöz hücreli karsinom modelinin geliştirilmesi
Ekici Y., Küçüksezer U. C., Bedeloğlu E., Erol B., Tuncer Kılınç F. N.
Uluslararası Katılımlı 17. Tıbbi Biyoloji ve Genetik Kongresi, İstanbul, Turkey, 28 - 31 October 2021, pp.335-336
2019
2019AIP mutasyon-negatif genç sporadik somatotropinomalı hastalarda MEN1 varyantlarının araştırılması
Tuncer Kılınç F. N., Soyluk Selçukbiricik Ö., Serbest E., Çiftçi S., Yarman E. S.
41.TEMHK, Türkiye, 27 Nisan 2019, Antalya, Turkey, 27 April - 01 May 2019, pp.157
2019
2019Whole Exome Sequence Analyses In A Consanguıneous Famıly Wıth Affected Dizygotic Twins Reveal A Novel SEPN1 Variant Associated With Multiminicore Disease
Sarı Tunel F., Tuncer Kılınç F. N., Bayrak A. E., Salman Yılmaz S., Oflazer P., Vural B.
13th Balkan Congress of Human Genetics, Edirne, Turkey, 17 - 20 April 2019, pp.76
2018
2018Does MEN1 variant (p.Ser183Cys) affect the response to DA therapy in a young prolactinoma patient without other components of MEN1 syndrome?
YENİDÜNYA YALIN G., TUNCER KILINÇ F. N., doğanşen s., YARMAN E. S.
Endobridge 2018, Antalya, Turkey, 25 - 28 October 2018, pp.9
2017
2017Towards an Epilepsy Biobank
Haryanyan G., Özdemir Ö., Yücesan E., TUNCER F. N., Kesim F. Y., ERBİLGİN Y., et al.
Global Biobank Week, 13 - 15 September 2017
2017
2017Outcomes of a Biobanking Initiative from Turkey: ‘Investing in the Future: BIOBANK
ERBİLGİN Y., TUNCER F. N., UĞUR İŞERİ S. A., Khodzhaev K., ÖZBEK U.
Global Biobank Week, 13 - 15 September 2017
2016
2016Investing in the Future BIOBANK
ERBİLGİN Y., TUNCER F. N., Haryanyan G., Khodzhaev K., UĞUR İŞERİ S. A., ÖZBEK U.
European Biobank Week 2016, 13 - 16 September 2016
Books & Book Chapters
2017
2017Biyobankalamada Etik Unsurlar
TUNCER F. N.
in: Biyobankalarda Etik ve Yasal Düzenlemeler Kılavuzu, Tuncer, F.N., Editor, İstanbul Tıp Kitabevleri, İstanbul, pp.1-11, 2017
Supported Projects
2022 - Continues
2022 - ContinuesHemoglobinopatilerde Okside Hemoglobin ve Mitokondriyal Hasar İlişkili Moleküler Paternler DAMPs ve NAD ile Antioksidanların İnvitro Potansiyel Terapötik Etkileri
Project Supported by Higher Education Institutions
KARAKAŞ Z. (Executive), ÖZBEÖZ O., TANYILDIZ H. G., GÖKÇAY G. F., ÖZHAN G., GEDİKBAŞI A., et al.
2014 - Continues
2014 - Continues
Tip 1 Diyabetin Rejeneratif tedavisi: Pankreatik Beta Hücre Prolifersyonuna Yönelik Yeni Teknoloji Geliştirilmesi
Other International Funding Programs
GÜROL A. O. (Executive), KÜÇÜKSEZER U. C., DENİZ G., TUNCER KILINÇ F. N.
2019 - 2021
2019 - 2021Valproik asitin Wnt sinyal yolağı üzerindeki etkilerinin PANC-1 ve HEK293 hücre hattında irdelenmesi
Project Supported by Higher Education Institutions
GÜROL A. O. (Executive), OLGUN H. B., EKİCİ F. Y., YILMAZ A., TUNCER KILINÇ F. N., KÜÇÜKSEZER U. C., et al.
2018 - 2021
2018 - 2021Ksenograft Fare Modelinde Oral Yassı Hücreli Karsinoma Hücrelerinin Büyümesi ve Metastazı Üzerine Düşük Molekül Ağırlıklı Heparinin Antineoplazik Etkinliğinin Değerlendirilmesi
Project Supported by Higher Education Institutions
TUNCER KILINÇ F. N. (Executive), KÜÇÜKSEZER U. C., AKÇA B. S., EKİCİ F. Y., SOLUK TEKKEŞİN M.
2018 - 2018
2018 - 2018Farklılaşmış PANC-1 hücrelerinde INSIG1 geninin incelenmesi
Project Supported by Higher Education Institutions
TUNCER KILINÇ F. N. (Executive), AYAZ M. S.
2017 - 2018
2017 - 2018Farklılaşmış pankreas karsinom hücrelerinde mikroarray sonuçlarının validasyonu
Project Supported by Higher Education Institutions
TUNCER KILINÇ F. N. (Executive), PODA M., HASANOĞULLARI B. G., AYAZ M. S., EKİCİ F. Y.
2016 - 2017
2016 - 2017
Diyabet modeli önerisi için PANC-1 hücre hattında aday gen dizilemelerinin gerçekleştirilmesi
Project Supported by Higher Education Institutions
TUNCER KILINÇ F. N. (Executive), PODA M., TEKGÜL Ş.
2015 - 2017
2015 - 2017Geleceğe Yatırım: BİYOBANKA
Project Supported by Other Official Institutions
TÜRKER ŞENER L., UĞUR İŞERİ S. A., TUNCER KILINÇ F. N., ERBİLGİN Y.
2015 - 2017
2015 - 2017Türk toplumundaki ailevi izole hipofiz adenomlarında ve genç sporadik hipofiz adenomlarında AIP ve MEN1 gen analizleri ile genetik yatkınlığın araştırılması
Project Supported by Higher Education Institutions
YARMAN E. S. (Executive), TUNCER F. N., SOYLUK SELÇUKBİRİCİK Ö.
2016 - 2016
2016 - 2016A novel mutation in PCDH19 enabled genetic diagnosis as Epilepsy and Mental Retardation Limited to Females
Project Supported by Higher Education Institutions
TUNCER KILINÇ F. N. (Executive), UĞUR İŞERİ S. A., ÖZBEK U., KARA B., MARAŞ GENÇ H., UYUR YALÇIN E.
2016 - 2016
2016 - 2016