Education
2010 - 2016
2010 - 2016Doctorate
Koc University, Instıtute Of Scıence, Department Of Computatıonal Engıneerıng (Interdıscıplınary), Turkey
2007 - 2010
2007 - 2010Postgraduate
Bogazici University, Instıtute Of Bıomedıcal Engıneerıng, Biomedical Engineering, Turkey
2002 - 2007
2002 - 2007Undergraduate
Bogazici University, Faculty Of Arts And Scıences, Department Of Molecular Bıology And Genetıcs, Turkey
Academic Positions
2021 - Present
2021 - PresentAssistant Professor
Istanbul University, Faculty of Science, Depertment of Biology
2017 - 2021
2017 - 2021Researcher
University of Michigan - Ann Arbor, Life Sciences Institute, Chemistry
Non Academic Experience
2017 - 2021
2017 - 2021Research Scholar (post-doc)
University of Michigan, Research Scholar (post-doc)
Articles
All (14)
SCI-E, SSCI, AHCI (13)
SCI-E, SSCI, AHCI, ESCI (13)
Scopus (13)
TRDizin (1)
2025
20251. Lack of Pseudouridine Synthase 7 Enzyme Sensitizes Yeast Cells to DNA-Damaging Agents
Tardu M.
Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi (Online)
, vol.8, no.4, pp.1613-1623, 2025 (TRDizin)
2024
20242. Conserved 5-methyluridine tRNA modification modulates ribosome translocation
Jones J. D., Franco M. K., Giles R. N., Eyler D. E., Tardu M., Smith T. J., et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
, vol.121, no.35, 2024 (SCI-Expanded, Scopus)
2022
20223. Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures
Purchal M. K., Eyler D. E., TARDU M., Franco M. K., Korn M. M., Khan T., et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
, vol.119, no.4, 2022 (SCI-Expanded, Scopus)
2021
20214. mRNA and tRNA modification states influence ribosome speed and frame maintenance during poly(lysine) peptide synthesis
Smith T. J., Tardu M., Khatri H. R., Koutmou K.
JOURNAL OF BIOLOGICAL CHEMISTRY
, vol.298, no.6, 2021 (SCI-Expanded, Scopus)
2019
20195. Identification and Characterization of a New Class of (6-4) Photolyase from Vibrio cholerae
Dikbas U. M., Tardu M., Canturk A., Gul Ş., Ozcelik G., Baris I., et al.
BIOCHEMISTRY
, vol.58, no.43, pp.4352-4360, 2019 (SCI-Expanded, Scopus)
2019
20196. Comparative RNA-seq analysis of the drought-sensitive lentil (Lens culinaris) root and leaf under short- and long-term water deficits
Morgil H., Tardu M., Cevahir G., Kavakli I. H.
FUNCTIONAL & INTEGRATIVE GENOMICS
, vol.19, no.5, pp.715-727, 2019 (SCI-Expanded, Scopus)
2019
20197. Cryptochrome deletion in p53 mutant mice enhances apoptotic and anti-tumorigenic responses to UV damage at the transcriptome level
Cavga A. D., Tardu M., Korkmaz T., Keskin O., Ozturk N., Gursoy A., et al.
FUNCTIONAL & INTEGRATIVE GENOMICS
, vol.19, no.5, pp.729-742, 2019 (SCI-Expanded, Scopus)
2019
20198. Identification and Quantification of Modified Nucleosides in Saccharomyces cerevisiae mRNAs
Tardu M., Jones J. D., Kennedy R. T., Lin Q., Koutmou K. S.
ACS CHEMICAL BIOLOGY
, vol.14, no.7, pp.1403-1409, 2019 (SCI-Expanded, Scopus)
2017
20179. Understanding lipid metabolism in high-lipid-producing Chlorella vulgaris mutants at the genome-wide level
Sarayloo E., Tardu M., Unlu Y. S., Simsek S., Cevahir G., Erkey C., et al.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
, vol.28, pp.244-252, 2017 (SCI-Expanded, Scopus)
2017
201710. MerR and ChrR mediate blue light induced photo-oxidative stress response at the transcriptional level in Vibrio cholerae
Tardu M., Bulut S., Kavakli I. H.
SCIENTIFIC REPORTS
, vol.7, 2017 (SCI-Expanded, Scopus)
2017
201711. The Photolyase/Cryptochrome Family of Proteins as DNA Repair Enzymes and Transcriptional Repressors
Kavakli I. H., Baris I., Tardu M., Gul Ş., Oner H., Cal S., et al.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
, vol.93, no.1, pp.93-103, 2017 (SCI-Expanded, Scopus)
2016
201612. RNA-seq analysis of the transcriptional response to blue and red light in the extremophilic red alga, Cyanidioschyzon merolae
Tardu M., Dikbas U. M., Baris I., Kavakli I. H.
FUNCTIONAL & INTEGRATIVE GENOMICS
, vol.16, no.6, pp.657-669, 2016 (SCI-Expanded, Scopus)
2016
201613. MILP-HYPERBOX CLASSIFICATION FOR STRUCTURE-BASED DRUG DESIGN IN THE DISCOVERY OF SMALL MOLECULE INHIBITORS OF SIRTUIN6
Tardu M., Rahim F., Kavakli I. H., Turkay M.
RAIRO-OPERATIONS RESEARCH
, vol.50, no.2, pp.387-400, 2016 (SCI-Expanded, Scopus)
2016
201614. Reduced Glucose Sensation Can Increase the Fitness of Saccharomyces cerevisiae Lacking Mitochondrial DNA
Akdogan E., Tardu M., Garipler G., Baytek G., Kavakli I. H., Dunn C. D.
PLOS ONE
, vol.11, no.1, 2016 (SCI-Expanded, Scopus)
Books
2018
20181. Kanserde DNA Tamiri Ve Tedavide DNA Tamir Yolakları
Kavaklı İ. H., Gül Ş., Tardu M., Barış İ.
in: Kanser Moleküler Biyolojisi, Yusuf Baran, Editor, Kısayol Yayıncılık, İstanbul, pp.173-184, 2018
Other Publications
2023
20231. tRNA Metiltransferaz Maya Mutantlarının Farklı Tuz Stresi Koşullarında Büyüme Karakteristiklerinin Tespit Edilmesi
Korkmaz A. A., Irez B. G., Vural S., Ceylan S., Tardu M.
Presentation, pp.82, 2023
Funded Projects
2023 - Present
2023 - Present
Yeni nesil RNA aşılarında kullanılan mRNA moleküllerinin saflığının arttırılmasına yönelik bir çalışma
Project Supported by Other Official Institutions
TARDU M. (Executive), TAŞKIN A. C., MORGİL GERÇEK H.
2024 - 2025
2024 - 2025Hücresel Stres Koşulları Altında Trm10 Enziminin Rolünün Transkriptom Düzeyinde Araştırılması
Project Supported by Higher Education Institutions , BAP MSc
TARDU M. (Executive), KORKMAZ A. A.
2024 - 2025
2024 - 2025mRNA Dizi ve Yapısal Özelliklerini Kullanarak Translasyon Verimliliğinin Makine Öğrenimi ile Tahmini
Emergency R&D Project of Group A
(Project Abstract)
TARDU M., Turgut Ç.(Executive)
2022 - 2025
2022 - 2025
Developing an mRNA-based vaccine platform against viral infections: A pilot study on SARS-CoV-2 pathogen
TUBITAK Project , 2232 - Dormitory Research Scholarship Program
Tardu M. (Executive), Morgil Gerçek H., Gerçek Y. C.
2024 - 2024
2024 - 2024
RNA-temelli Aşı ve Terapötiklerin Geliştirilmesi Kapsamında RNA Biyolojisi Araştırmaları Laboratuvarı Altyapısı Sürekliliği Desteği
Project Supported by Higher Education Institutions , BAP Other
TARDU M. (Executive), DEMİR Z., ARSLAN S., TURGUT Ç., ÖZDEMİR M. D., KORKMAZ A. A., et al.
2023 - 2024
2023 - 2024Saccharomyces cerevisiae Trm1 ve Trm10 enzim mutantlarında yüksek tuz stresi kaynaklı gen seviyelerinin qPCR yöntemi ile tespit edilmesi
Project Supported by Higher Education Institutions , BAP Other
TARDU M. (Executive), CEYLAN S., AKYIL E. C., VURAL S., KORKMAZ A. A.
2022 - 2024
2022 - 2024Engineering Microalgae To Enhance Lipid Productivities For Industrial Scale Biodiesel Production
H2020 Project , CSA Marie Skłodowska-Curie Coordination and Support Actions Project
Tardu M. (Executive)
Scholarships
2017 - 2021
2017 - 2021Post Doctoral Research Fellow
University
2010 - 2016
2010 - 2016