Yayınlar & Eserler

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SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Novel 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide based thiosemicarbazides as potent and selective inhibitors of tumor-associated human carbonic anhydrase IX and XII: Synthesis, cytotoxicity, and molecular modelling studies

Demir Yazıcı K., Trawally M., Bua S., Öztürk-Civelek D., Akdemir A., Supuran C. T., et al.
Bioorganic Chemistry , cilt.144, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier

Thiosemicarbazone-benzenesulfonamide Derivatives as Human Carbonic Anhydrases Inhibitors: Synthesis, Characterization, and In silico Studies

Trawally M., DEMİR YAZICI K., Angeli A., Kaya K., Akdemir A., Supuran C. T., et al.
Anti-Cancer Agents in Medicinal Chemistry , cilt.24, sa.9, ss.649-667, 2024 (SCI-Expanded) identifier identifier identifier

Urease inhibitors for the treatment of H. pylori

GÜZEL AKDEMİR Ö., Akdemir A.
Expert Opinion on Therapeutic Patents , 2024 (SCI-Expanded) identifier identifier

Dithiocarbamates and dithiocarbonates containing 6-nitrosaccharin scaffold: Synthesis, antimycobacterial activity and in silico target prediction using ensemble docking-based reverse virtual screening

Trawally M., Demir Yazıcı K., İpek Dingiş-Birgül S., Kaya K., Akdemir A., Güzel Akdemir Ö.
Journal of Molecular Structure , cilt.1277, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier

Mandelic acid-based spirothiazolidinones targeting M. tuberculosis: Synthesis, in vitro and in silico investigations

Trawally M., Demir-Yazici K., Dingiş Birgül S. İ., Kaya K., Akdemir A., Güzel-Akdemir Ö.
BIOORGANIC CHEMISTRY , cilt.121, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier

New Pyridinium Salt Derivatives of 2-(Hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide as Selective Inhibitors of Tumour-Related Human Carbonic Anhydrase Isoforms IX and XII

Güzel Akdemir Ö., Demir Yazıcı K., Vullo D., Supuran C. T., Akdemir A.
Anti-Cancer Agents in Medicinal Chemistry , cilt.22, sa.14, ss.2637-2646, 2022 (SCI-Expanded) identifier identifier identifier

Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII

Akocak S., Guzel-Akdemir O., Sanku R. K. K., Russom S. S., Iorga B. I., Supuran C. T., et al.
BIOORGANIC CHEMISTRY , cilt.103, 2020 (SCI-Expanded) identifier identifier identifier

Synthesis and antibacterial activity of new hybrid derivatives of 5-sulfamoyl-1H-indole and 4-thiazolidinone groups

Guzel-Akdemir O., Trawally M., Ozbek-Babuc M., Ozbek-Celik B., Ermut G., Ozdemir H.
MONATSHEFTE FUR CHEMIE , cilt.151, ss.1443-1452, 2020 (SCI-Expanded) identifier identifier

Novel Indole-Based Hydrazones as Potent Inhibitors of the alpha-class Carbonic Anhydrase from Pathogenic Bacterium Vibrio cholerae

Demir-Yazici K., Guzel-Akdemir Ö., Angeli A., Supuran C. T., Akdemir A.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , cilt.21, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier

Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors

Guezel-Akdemir Ö., Carradori S., Grande R., Demir-Yazici K., Angeli A., Supuran C. T., et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , cilt.21, sa.8, 2020 (SCI-Expanded) identifier identifier identifier

Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII

Demir-Yazici K., Bua S., Akgunes N. M., Akdemir A., Supuran C. T., Guzel-Akdemir O.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , cilt.20, 2019 (SCI-Expanded) identifier identifier identifier

Novel thiazolidinone-containing compounds, without the well-known sulphonamide zinc-binding group acting as human carbonic anhydrase IX inhibitors

Guzel-Akdemir O., Angeli A., Demir K., Supuran C. T., AKDEMİR A.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.33, sa.1, ss.1299-1308, 2018 (SCI-Expanded) identifier identifier identifier

Isatin analogs as novel inhibitors of Candida spp. beta-carbonic anhydrase enzymes

Akdemir A., Guzel-Akdemir O., Karali N. L., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.24, sa.8, ss.1648-1652, 2016 (SCI-Expanded) identifier identifier identifier

Discovery of novel isatin-based sulfonamides with potent and selective inhibition of the tumor-associated carbonic anhydrase isoforms IX and XII

Guzel-Akdemir O., AKDEMİR A., Karali N., Supuran C. T.
ORGANIC & BIOMOLECULAR CHEMISTRY , cilt.13, sa.23, ss.6493-6499, 2015 (SCI-Expanded) identifier identifier identifier

Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition

Guzel-Akdemir O., Biswas S., Lastra K., McKenna R., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.21, sa.21, ss.6674-6680, 2013 (SCI-Expanded) identifier identifier identifier

Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides

AKDEMİR A., Guzel-Akdemir O., Scozzafava A., Capasso C., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.21, sa.17, ss.5228-5232, 2013 (SCI-Expanded) identifier identifier identifier

A Class of Sulfonamides with Strong Inhibitory Action against the alpha-Carbonic Anhydrase from Trypanosoma cruzi

Guzel-Akdemir O., AKDEMİR A., Pan P., Vermelho A. B., Parkkila S., Scozzafava A., et al.
JOURNAL OF MEDICINAL CHEMISTRY , cilt.56, sa.14, ss.5773-5781, 2013 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier

o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII

Guzel-Akdemir O., Akdemir A., Işık S., Vullo D., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.21, ss.1386-1391, 2013 (SCI-Expanded) identifier identifier identifier

Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms

Biswas S., Aggarwal M., GÜZEL Ö., Scozzafava A., McKenna R., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.19, 2011 (SCI-Expanded)

Carbonic anhydrase inhibitors. The ß-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides

GÜZEL Ö., Maresca A., Hall R. A., Scozzafava A., Mastrolorenzo A., Mühlschlegel F. A., et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , cilt.20, ss.2508-2511, 2010 (SCI-Expanded)

3-Phenyl-1H-Indole-5-Sulfonamides: Structure-Based Drug Design of a Promising Class of Carbonic Anhydrase Inhibitors

Guzel O., Innocenti A., Vullo D., Scozzafava A., Supuran C. T.
CURRENT PHARMACEUTICAL DESIGN , cilt.16, sa.29, ss.3317-3326, 2010 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier

Synthesis and biological evaluation of new 4-thiazolidinone derivatives

Guzel O., Salman A.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.24, sa.4, ss.1015-1023, 2009 (SCI-Expanded) identifier identifier identifier

Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB

Guzel O., Innocenti A., Scozzafava A., Salman A., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.17, sa.14, ss.4894-4899, 2009 (SCI-Expanded) identifier identifier identifier

Discovery of Low Nanomolar and Subnanomolar Inhibitors of the Mycobacterial beta-Carbonic Anhydrases Rv1284 and Rv3273

Guzel O., Maresca A., Scozzafava A., Salman A., Balaban A. T., Supuran C. T.
JOURNAL OF MEDICINAL CHEMISTRY , cilt.52, sa.13, ss.4063-4067, 2009 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier

Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitchondrial isoforms VA and VB

GÜZEL Ö., Innocenti A., Scozzafava A., Salman A., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.17, ss.4894-4899, 2009 (SCI-Expanded)

Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors

GÜZEL Ö., Innocenti A., Scozzafava A., Salman A., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , cilt.19, ss.3170-3173, 2009 (SCI-Expanded)

Carbonic anhydrase inhibitors. The nematode alpha-carbonic anhydrase of Caenorhabditis elegans CAH-4b is highly inhibited by 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides

Guzel O., Innocenti A., Hall R. A., Scozzafava A., Muhlschlegel F. A., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.17, sa.8, ss.3212-3215, 2009 (SCI-Expanded) identifier identifier identifier

Carbonic anhydrase inhibitors. Synthesis of 2,4,6-trimethylpyridinium derivatives of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides acting as potent inhibitors of the tumor-associated isoform IX and XII

GÜZEL Ö., Maresca A., Scozzafava A., Salman A., Balaban A. T., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , cilt.19, ss.2931-2934, 2009 (SCI-Expanded)

Crystal Structure of 1,1,3-trioxo-2,3-dihydro-1,2-benzisothiazol-2-ylmethyl 4-phenyl Piperazine-1-carbodithioate, C19H19N3O3S3.

AKKURT M., Yalcin S. P., Guzel O., Salman A., BÜYÜKGÜNGÖR O.
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES , cilt.65, 2009 (SCI-Expanded) identifier

Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies

GÜZEL Ö., Temperini C., Innocenti A., Scozzafava A., Salman A., Supuran C. T.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , cilt.18, ss.152-158, 2008 (SCI-Expanded)

Synthesis and antituberculosis activity of 5-methyl/trifluoromethoxy-1H-indole-2,3-dione 3-thiosemicarbazone derivatives

Guzel O., Karali N., Salman A.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.16, sa.19, ss.8976-8987, 2008 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier

N-(2,6-dimethyl-3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-2-hydroxy-2,2-diphenylacetamide

Yalcin S. P., AKKURT M., ŞAHİN E., Guzel O., Salman A., Ihan E.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE , cilt.64, 2008 (SCI-Expanded) identifier identifier identifier

Carbonic anhydrase inhibitors. Synthesis and inhibition studies against mammalian isoforms I – XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides

GÜZEL Ö., Innocenti A., Scozzafava A., Salman A., Parkkila S., Hilvo M., et al.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.16, ss.9113-9120, 2008 (SCI-Expanded)

Synthesis and antituberculosis activity of 5-methyl/trifluoromethoxy-1H-indole-2,3-dione-3-thiosemicarbazone derivatives

GÜZEL Ö., Karalı N., Salman A.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.16, ss.8976-8987, 2008 (SCI-Expanded)

Crystal structure of (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl O-propyl dithiocarbonate

Akkurt M., Yalçın Ş. P., Büyükgüngör O., GÜZEL Ö., Salman A.
ANALYTICAL SCIENCES , cilt.24, 2008 (SCI-Expanded)

1,1,3-Trioxo-2,3-dihydro-1,2-benzisothiazol-2-ylmethyl 4-phenylpiperazine-1-carbodithioate

Akkurt M., Yalçın Ş. P., GÜZEL Ö., Salman A., Büyükgüngör O.
Acta Crystallographica , cilt.E63, 2007 (SCI-Expanded)

N-(2,6-dimethyl-3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-2-hydroxy-2,2-diphenylacetamide

Yalçın Ş. P., Akkurt M., Şahin E., GÜZEL Ö., Salman A., İlhan E.
Acta Crystallographica , cilt.E64, 2007 (SCI-Expanded)

O-Butyl S-(1,1,3-trioksobenz[d]isothiazol-2-yl)methyl dithiocarbonate

Akkurt M., Karaca S., Şahin E., GÜZEL Ö., Salman A.
Acta Crystallographica , cilt.E63, 2007 (SCI-Expanded)

2-Hydroxy-N-(3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-2,2-diphenylacetamide.

Akkurt M., Karaca S., Şahin E., GÜZEL Ö., Salman A., İlhan E.
Acta Crystallographica , cilt.E63, 2007 (SCI-Expanded)

Synthesis, antimycobacterial and antitumor activities of new (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl N,N-disubstituted dithiocarbamate/O-alkyldithiocarbonate derivatives

Guzel O., Salman A.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.14, sa.23, ss.7804-7815, 2006 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier
Diğer Dergilerde Yayınlanan Makaleler

Role of human carbonic anhydrase isoforms VA and VB in obesity: Implications, mechanisms, and therapeutic prospects

Kaçmaz M., Trawally M., GÜZEL AKDEMİR Ö.
Journal of Research in Pharmacy , cilt.28, sa.3, ss.733-748, 2024 (ESCI) Creative Commons License identifier identifier

Antiviral Properties of 5-Sulfamoyl-1H-Indole-Linked Spirothiazolidinone Derivatives: A Study on Human Parainfluenza Virus-2

Trawally M., YILMAZ F. N., ÖZBEK ÇELİK B., Akdemir A., GÜZEL AKDEMİR Ö.
Journal of Research in Pharmacy , cilt.28, sa.1, ss.213-224, 2024 (ESCI) Creative Commons License identifier

Evaluation of some o-benzenedisulfonimido– sulfonamide derivatives as potent antimicrobial agents

Demir Yazıcı K., Yılmaz F. N., Özbek Çelik B., Güzel Akdemir Ö.
Istanbul Journal of Pharmacy , cilt.52, sa.3, ss.297-301, 2022 (Hakemli Dergi)

Synthesis and potential antitumor activities of mandelic acid linked 2-aryl-1,3-thiazolidin-4-ones

Demir-Yazici K., Guzel-Akdemir O.
JOURNAL OF RESEARCH IN PHARMACY , cilt.26, sa.4, ss.931-940, 2022 (ESCI) Sürdürülebilir Kalkınma identifier identifier identifier

Benzilic acid based new 2-aryl-1,3-thiazolidin-4-one derivatives: Synthesis and anticancer activity

Güzel Akdemir Ö., Demir-Yazıcı K.
JOURNAL OF RESEARCH IN PHARMACY , cilt.25, sa.3, ss.305-317, 2021 (ESCI)

Evaluation of new 2-hydroxy-N-(4-oxo-2-substituted phenyl-1,3-thiazolidin-3-yl)-2-phenylacetamide derivatives as potential antimycobacterial agents

GÜZEL AKDEMİR Ö., DEMİR YAZICI K., TRAWALLY M., DİNGİŞ BİRGÜL S. İ., Akdemir A.
Organic Communications , cilt.13, sa.2, ss.33-50, 2020 (ESCI) identifier identifier

Antimicrobial and antiviral activity of spiroindolinones bearing benzothiazolines moiety

Güzel Ö., Karalı N. L., Ermut G., Birteksöz Tan A. S.
ISTANBUL JOURNAL OF PHARMACY , cilt.43, sa.1, ss.1-11, 2013 (ESCI)

Spectrophotometric determination of drugs having primary amine group with p-dimethylaminocinnamaldehyde

GÜZEL Ö., Salman A.
TURKİSH JOURNAL OF PHARMACEUTİCAL SCİENCES , cilt.4(1), ss.31-39, 2007 (Scopus)
Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

4-Tiyazolin Türevleri: Kolon ve Meme Kanseri Tedavisi İçin Potansiyel Adaylar Olarak. Tümörle İlişkili hCA IX/XII İnhibitörleri

TRAWALLY M., GÜZEL AKDEMİR Ö.
VII. Ulusal Farmasötik Kimya Kongresi, Ege University, İzmir, October 26-28, 2024., İzmir, Türkiye, 26 Ekim 2024

4-Thiazoline Derivatives: Tumor-Associated HCA IX/XII Inhibitors as Potential Candidates for Colon and Breast Cancer Therapy.

TRAWALLY M., GÜZEL AKDEMİR Ö.
11th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS), Rome, Italy, September 5 - 6, 2024., Rome, İtalya, 5 - 06 Eylül 2024

Thione or Thiol: Sructural confirmation of (E)-2-(1-(4-cyanophenyl)ethylidene)-N-(2-fluoro-4-sulfamoylphenyl)hydrazine-1-carbothioamide and carbonic anhydrase inhibition studies

Guliyeva L., M. T., GÜZEL AKDEMİR Ö.
8th International Students Science Congress, Türkiye, 27 Nisan 2024

Synthesis, FTIR spectrum, experimental and theoretical crystal studies, and carbonic anhydrase inhibition studies on 2-[(1H-Pyrrol-2-yl)methylidene]-N-(3-sulfamoylphenyl)hydrazine-1-carbothioamide

TRAWALLY M., DEMİR YAZICI K., KAYA K., AKDEMİR A., GÜZEL AKDEMİR Ö.
12th Internation Drug Chemistry Conferences, Antalya, Türkiye, 07 Mart 2024

Development of Selective Inhibitors for the Tumor-Associated Carbonic Anhydrases

AKDEMİR A., DEMİR YAZICI K., M. T., GÜZEL AKDEMİR Ö.
8th International Conference Modern Trends in Physics, Baku, Azerbaycan, 30 Kasım 2023

Modification of SLC-0111 as Novel Carbonic Anhydrase Inhibitors

Guliyeva L., M. T., DEMİR YAZICI K., GÜZEL AKDEMİR Ö.
8th International Conference Modern Trends in Physics, Baku, Azerbaycan, 30 Kasım 2023

Novel sulfa drug containing thiourea derivatives: Synthesis, molecular modelling and inhibition studies of pharmaceutically important carbonic anhydrase isoforms

M. T., DEMİR YAZICI K., AKDEMİR A., GÜZEL AKDEMİR Ö.
10th Internation Drug Chemistry Conferences, Türkiye, 10 - 13 Mart 2023

Molecular Modeling Studies on Dithiocarbamates and Dithiocarbonates Containing 6-nitrosaccharin Scaffold as antitubercular agents

DİNGİŞ BİRGÜL S. İ., M. T., DEMİR YAZICI K., GÜZEL AKDEMİR Ö., AKDEMİR A.
10th Internation Drug Chemistry Conferences, Türkiye, 10 Mart 2022

SYNTHESIS AND HUMAN CARBONIC ANHYDRASE INHIBITION STUDIES OF SOME 1,3,4-THIADIAZOLES

Demir Yazıcı K., Güzel Akdemir Ö.
13th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Türkiye, 22 - 25 Haziran 2021, ss.309

Mandelic acid-based novel spirothiazolidinones: Synthesis, antimycobacterial activity and molecular modelling studies

M. T., DEMİR YAZICI K., DİNGİŞ BİRGÜL S. İ., GÜZEL AKDEMİR Ö., AKDEMİR A.
13th International Symposium on Pharmaceutical Sciences, 22 - 24 Haziran 2021

Synthesis and Antimycobacterial Activities of New Dithiocarbamates and Dithiocarbonates Containing 6-nitrosaccharin Scaffold

M. T., GÜZEL AKDEMİR Ö.
9th Internation Drug Chemistry Conferences, Türkiye, 8 - 11 Nisan 2021

NOVEL THIOSEMICARBAZONES-BASED BENZENESULFONAMIDE hCAII INHIBITORS: SYNTHESIS, BIOLOGICAL EVALUATION AND DOCKING STUDIES

Trawally M., Demir Yazıcı K., Güzel Akdemir Ö., Akdemir A.
3rd INTERNATIONAL AFRICAN CONFERENCE ON CURRENT STUDIES, 27 Şubat - 28 Ağustos 2021, ss.718

The Ongoing Quest for Selective hCA IX/XII Inhibitors

GÜZEL AKDEMİR Ö., M. T., DEMİR YAZICI K., AKDEMİR A., Angeli A., Supuran C. T.
8th Internation Drug Chemistry Conferences, Türkiye, 27 Şubat - 01 Mart 2020

Synthesis and Inhibitory Activity of 2-(alkylidene/arylidene)-N-(2-(non) substituted-3/4-sulfamoylphenyl)hydrazine-1-carbothioamide Derivatives Tumor-Associated Carbonic Anhydrase hCA IX and hCA XII Inhibitors

Trawally M., Demir Yazıcı K., Güzel Akdemir Ö.
8th Internation Drug Chemistry Conference, Antalya, Türkiye, 27 Şubat - 01 Mart 2020, ss.235

Inhibition of the α-class Carbonic Anhydrase from Vibrio cholera(VchCA) with Novel Sulfonamido based Hydrozones

Güzel Akdemir Ö., Demir Yazıcı K.
8th Interntional Drug Chemistry Conference, Antalya, Türkiye, 27 Şubat - 01 Mart 2020, ss.69

New Sulfonamidoindole Based Hydrazones as Potent and Selective Inhibitors of Tumour-Related Human Carbonic Anhydrase IX and XII Isoforms

DEMİR YAZICI K., Bua S., Akdemir A., Supuran C., GÜZEL AKDEMİR Ö.
4th Satellite International Meeting on Carbonic Anhydrase, Parma, İtalya, 14 - 17 Kasım 2019, cilt.1, sa.1, ss.11

Design and synthesis of novel indole based hydrazones containing sulfonamide moiety as selective inhibitors of tumour-associated carbonic anhydrase isoforms IX and XII

DEMİR YAZICI K., Bua S., Akdemir A., Supuran C., GÜZEL AKDEMİR Ö.
4th Satellite International Meeting on Carbonic Anhydrase, Parma, İtalya, 14 - 17 Kasım 2019, cilt.1, sa.1, ss.10

Tiyazolidinon iskeleti taşıyan bazı yeni bileşiklerin sentezi, yapılarının aydınlatılması ve antikanser aktivitelerinin incelenmesi

DEMİR YAZICI K., GÜZEL AKDEMİR Ö.
2. Ulusal Marmara Eczacılık Kongresi (UMEK-2018), İstanbul, Türkiye, 14 - 16 Kasım 2018, ss.111

Molecular modelling studies to guide synthesis programs of new thiourea compounds as putative inhibitors of hCA IX/XII and VcCA.

DEMİR K., Güzel Akdemir Ö., Karalı N., Akdemir A.
3rd Satellite Meeting on Carbonic Anhydrase, Montecatini Terme, İtalya, 24 - 27 Mayıs 2017, ss.68

Structurally novel thiazolidinone-containing compounds that do not contain sulfonamide groups display antifungal activity

GÜZEL AKDEMİR Ö., Carradori S., Rivanera D., Çapan G., Akdemir A.
3rd Satellite Meeting on Carbonic Anhydrase, Montecatini Terme, İtalya, 24 - 27 Mayıs 2017, ss.69

1H-indole-2,3-dione 3-[N-(4-sulfamoylphenyl)thiosemicarbazone] derivatives as putative anticancer and antifungal agents

Akdemir A., KARALI N. L., Supuran C. T., GÜZEL AKDEMİR Ö.
7th European Congress of Pharmacology EPHAR 2016, İstanbul, Türkiye, 27 - 30 Haziran 2016, ss.1

Substituted-phenylacetamido aromatic sulfonamides are potent inhibitors of human and Trypanosoma cruzi carbonic anhydrases

GÜZEL AKDEMİR Ö., Akdemir A., Pan P., Vermelho A. B., Parkkila S., Scozzafava A., et al.
10th International Carbonic Anhydrase Conference, Maastricht, Hollanda, 20 - 22 Nisan 2015, ss.48 Sürdürülebilir Kalkınma

Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides

Güzel Akdemir Ö., Akdemir A., Scozzafava A., Cappaso C., Supuran C. T.
Frontiers in CA research Dissemination Activity of the EU Project Metoxia, Pistoia, İtalya, 18 - 20 Nisan 2015, ss.1

Potent Inhibitors of Mitochondrial Carbonic Anhydrase Isozyme CA-VA and CA-VB and brain associated isozyme CA-VII

Akdemir A., GÜZEL Ö., Supuran C.
9th International Conference on the Carbonic Anhydrases, Antalya, Türkiye, 11 - 15 Nisan 2012, ss.67

Synthesis and Pharmacological Evaluation of New Series of 3-Phenyl-1H-indole-5-Sulfonamides as Promising Carbonic Anhydrase Inhibitors

Güzel Akdemir Ö.
9th International Conference on the Carbonic Anhydrases, Antalya, Türkiye, 11 - 15 Nisan 2012, ss.35

Pyridinium Derivatives of 3-Aminobenzensulfonamide-Structure-Activity Relationship as Carbonic Anhydrase Inhibitors

Akocak S., GÜZEL Ö., Supuran C., Ilies M. A.
9th International Conference on the Carbonic Anhydrases, Antalya, Türkiye, 11 - 15 Nisan 2012, ss.84

5-triflorometoksi-1H-İndol-2,3-Dion 3-Tiyosemikarbazon Türevlerinin Miyeloid, Lenfoid Lösemi Hücreleri ve Akut Lenfoblastik Lösemi Hastalarının Periferik Kan Mononuklear Hücreleri Üzerine Sitotoksik Etkileri.

Çetin M. B., Karadenizli S., Kuruca D. S., Karalı N. L., Güzel Akdemir Ö., Akgün Dar K., et al.
III. Multidisipliner Kanser Araştırma Sempozyumu Teorik Metot Çalıştayı, Bursa, Türkiye, 14 - 17 Mart 2010, ss.40

Carbonic anhydrase inhibitors. The nematode ?-carbonic anhydrase of Caenorhabditis elegans CAH-4b is highly inhibited by 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides

GÜZEL Ö., Innocenti A., Hall R. A., Scozzafava A., Mühlschlegel F. A., Supuran C.
8th International Conference on the Carbonic Anhydrases, Floransa, İtalya, 16 - 19 Eylül 2009, ss.43

Synthesis and biological evaluation of new 6-nitrosaccharin derivatives

GÜZEL Ö., Salman A.
9th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Türkiye, 23 - 26 Haziran 2009, ss.190

Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial ?-carbonic anhydrases Rv1284 and Rv3273

GÜZEL Ö., Maresca A., Scozzafava A., Salman A., Balaban A. T., Supuran C.
9th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Türkiye, 23 - 26 Haziran 2009, ss.188

Synthesis of new 4-thiazolidinone derivatives as potential antimycobacterial and antitumor agents

GÜZEL Ö., Salman A.
3rd International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-3), Antalya, Türkiye, 16 - 21 Ekim 2007, ss.70

Synthesis and antimycobacterial activity of new 4-thiazolidinone derivatives

GÜZEL AKDEMİR Ö., Salman A., ÇAPAN G.
3rd International Meeting on Medicinal and Pharmaceutical Chemistry, Antalya, Türkiye, 16 - 21 Ekim 2007, ss.1

Synthesis antimycobacterial and antitumor activities of new5-bromo-N-(3-oxo-1-thia-4-azaspiro[4.4]non-4-yl)/N-(3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide derivatives

GÜZEL AKDEMİR Ö., ÇAPAN G., Salman A.
5 th International Symposium on Pharmaceutical Chemistry, İstanbul, Türkiye, 5 - 07 Eylül 2007, ss.57

Synthesis, characterization and antituberculosis activity of spiroindolinones

Karalı N., GÜZEL Ö., Salman A.
5th International symposium on Pharmaceutical Chemistry, İstanbul, Türkiye, 5 - 07 Eylül 2007, ss.80

One-pot synthesis synthesis of novel substituted 4-(3,4-dimethoxyphenyl)ethyl-1-thia-4-azaspiro[4.5]decan-3-ones

GÜZEL Ö., Terzioğlu N., Gürsoy A.
3rd International Conference on Multi-Component Reactions and Related Chemistry, Amsterdam, Hollanda, 9 - 13 Temmuz 2006, ss.87

One-pot synthesis of novel substituted 4-morpholinoethyl-1-thia-4-azaspiro[4.5]decan-3-one

Terzioğlu N., GÜZEL Ö., Gürsoy A.
3rd International Conference on Multi-Component Reactions and Related Chemistry, Amsterdam, Hollanda, 9 - 13 Temmuz 2006, ss.129

Synthesis, antimycobacterial and antitumor activities of new (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl N,N-disubstituted dithiocarbamate / O-alkyldithiocarbonate derivatives

Güzel Akdemir Ö., Salman A.
International Symposium on Medicinal Chemistry Research and Development, MCRD 2005, Aydın, Türkiye, 28 Eylül - 01 Ekim 2005, ss.44

New 2-hydroxy-N-(4-oxo-2-substituted phenyl-1,3-thiazolidin-3-yl)-2-phenylacetamide derivatives: synthesis and antimicrobial evaluation

GÜZEL Ö., Salman A., Terzioğlu N., Çapan G.
2ND International Meeting on Medicinal and Pharmaceutical Chemistry IMMPC-2, Antalya, Türkiye, 10 Ekim 2004 - 14 Ekim 2002, ss.141

Synthesis and antimicrobial evaluation of new 2-hydroxy-N-(4-oxo-2-substituted phenyl-1,3-thiazolidine-3-yl)-2-phenylacetamide derivatives

GÜZEL AKDEMİR Ö., Salman A., ÇAPAN G.
4th International Symposium on Pharmaceutical Chemistry, İstanbul, Türkiye, 17 - 19 Eylül 2003, ss.169

Spectrophotometric determination of some drugs incorporating primary amino functions

GÜZEL Ö., Salman A.
1st International Meeting on Medicinal and Pharmaceutical Chemistry IMMPC-1, Ankara, Türkiye, 25 - 28 Eylül 2002, ss.78

Synthesis and antimycobacterial activity of new 2-hydroxy-N-(3-oxo-1-thia-4-azaspiro[4.4]non-4-yl)/(3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-2-phenyl-acetamide derivatives

GÜZEL Ö., Çapan G., İlhan E., Salman A.
1st International Meeting on Medicinal and Pharmaceutical Chemistry IMMPC-1, Ankara, Türkiye, 25 - 28 Eylül 2002, ss.79
Kitap & Kitap Bölümleri

Aromatase

GÜZEL AKDEMİR Ö.
Metalloenzymes, Claudiu T. Supuran, William A. Donald, Editör, Academic Press is an imprint of Elsevier, ss.459-464, 2023

Piperine Derivatives: New Trends in Medicinal Chemistry

Trifan A., GÜZEL AKDEMİR Ö., CARRADORİ S.
Medicinal Chemistry Lessons From Nature (Volume 3) Alkaloids and Other Nitrogen-Containing Derivatives, Simone Carradori, Editör, Bentham Science Publishers Pte. Ltd. 80 Robinson Road #02-00, Singapore 068898, Singapore2023, ss.100-127, 2023

İlaç Tasarımı: hedef protein ile etkileşim optimizasyonu

GÜZEL AKDEMİR Ö., AKDEMİR A.
Medisinal Kimya Giriş, Prof.Dr. Özekin Algül, Editör, Ankara Nobel Tıp Kitapevi, Ankara, ss.223-255, 2021

Antibakteriyel Sülfa İlaçları

GÜZEL AKDEMİR Ö.
Medisinal Kimya, Mehmet Alp, Editör, Akademisyen Kitabevi, Ankara, ss.244-264, 2021

Foye Medisinal Kimya Temel İlkeler

GÜZEL AKDEMİR Ö., AKDEMİR A.
Ankara Nobel, 2019

Antipsikotik ve Anksiyolitik İlaçlar

Güzel Akdemir Ö., Akdemir A.
Foye Medisinal Kimya Temel İlkeleri, Öztekin Algül,Kayhan Bolelli, Editör, Nobel Yayın Dağıtım, Ankara, ss.96-113, 2019

The Structure, Physiological Role, and Potential Medicinal Applications of Carbonic Anhydrase V

AKDEMİR A., GÜZEL AKDEMİR Ö.
Carbonic Anhydrases as Biocatalysts from Theory to Medical and Industrial Applications, Supuran Claudiu, Simone Giuseppina, Editör, Radarweg 29, PO Box 211, 1000 AE Amsterdam, The NetherlandsThe Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, UK225 Wyman Street, Waltham, MA 02451, USA, ss.125-139, 2015
Metrikler

Yayın

96

Atıf (WoS)

918

H-İndeks (WoS)

14

Atıf (Scopus)

1070

H-İndeks (Scopus)

21

Atıf (Scholar)

1321

H-İndeks (Scholar)

23

Atıf (TrDizin)

1

H-İndeks (TrDizin)

1

Proje

22

Fikri Mülkiyet

1

Tez Danışmanlığı

3

Açık Erişim

2
BM Sürdürülebilir Kalkınma Amaçları