Metrics
Publication
23
UN Sustainable Development Goals
Education
2016 - 2022
2016 - 2022Doctorate
Istanbul University, Institute of Graduate Studies In Sciences, Moleküler Biyoloji Ve Genetik, Turkey
2014 - 2016
2014 - 2016Postgraduate
Tokat Gaziosmanpaşa University, Faculty Of Engıneerıng And Natural Scıences, Turkey
2010 - 2014
2010 - 2014Undergraduate
Tokat Gaziosmanpaşa University, Faculty Of Engıneerıng And Natural Scıences, Turkey
Dissertations
2016
2016Postgraduate
VİRAL TANI KİTLERİNİN GELİŞTİRİLMESİ İÇİN MOLONEY MURİNE LEUKEMİA VİRUS (MMLV) REVERS TRANSKRİPTAZ ENZİMİNİN REKOMBİNANT OLARAK ÜRETİLMESİ
Tokat Gaziosmanpaşa University, Graduate School Of Natural And Applıed Scıences
Research Areas
Life Sciences
Molecular Biology and Genetics
Genetic Engineering
Natural Sciences
Academic Positions
2016 - Present
2016 - PresentResearch Assistant
Istanbul University, Institute of Graduate Studies In Sciences, Moleküler Biyoloji Ve Genetik
2016 - 2019
2016 - 2019Research Assistant
Alanya Alaaddin Keykubat University, Faculty Of Engıneerıng, Department Of Bıoengıneerıng
2015 - 2016
2015 - 2016Research Assistant
Tokat Gaziosmanpaşa University, Faculty Of Engıneerıng And Natural Scıences
Articles
All (18)
SCI-E, SSCI, AHCI (8)
SCI-E, SSCI, AHCI, ESCI (11)
ESCI (3)
Scopus (9)
TRDizin (6)
Other Publications (3)
2025
20251. Enhancing transfection efficiency of primary cell lines using different terminated PBAE structures without endcapping reaction
Demir I., Küçükertuğrul Çelik S., BAL K., Kaplan Ö., Şentürk S., DEMİR K., et al.
Colloid and Polymer Science
, vol.303, no.8, pp.1705-1719, 2025 (SCI-Expanded)
2024
20242. Development of recombinant protein-based nanoparticle systems for inducing tumor cell apoptosis: In vitro evaluation of their cytotoxic and apoptotic effects on cancer cells
Kaplan Ö., GÖK M. K., PEKMEZ M., Erden Tayhan S., Özgümüş S., Gökçe İ., et al.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
, vol.95, 2024 (SCI-Expanded)
2024
20243. Green synthesized silver nanoparticles with mushroom extracts of Paxina leucomelas and Rhizopogon luteolus induce ROS-Induced intrinsic apoptotic pathway in cancer cells
Tosun N. G., KAPLAN Ö., Imamoglu R., Turkekul I., Gokce I., Ozgur A.
INORGANIC AND NANO-METAL CHEMISTRY
, vol.54, no.11, pp.1057-1066, 2024 (SCI-Expanded)
2023
20234. Thiolated α-cyclodextrin: The likely smallest drug carrier providing enhanced cellular uptake and endosomal escape
Kaplan Ö., Truszkowska M., Kali G., Knoll P., Blanco Massani M., Braun D. E., et al.
Carbohydrate Polymers
, vol.316, 2023 (SCI-Expanded)
2023
20235. Green synthesis of silver nanoparticles using Macrolepiota procera extract and investigation of their HSP27, HSP70, and HSP90 inhibitory potentials in human cancer cells
Ozgur A., KAPLAN Ö., Tosun N. G., Turkekul I., Gokce I.
PARTICULATE SCIENCE AND TECHNOLOGY
, vol.41, no.3, pp.330-340, 2023 (SCI-Expanded)
2022
20226. Polymer-Based Transfection Agents Used in CRISPR-CAS9 System
İmamoğlu R., Kaplan Ö., Gök M. K., Gökçe İ.
Turkish Journal of Nature and Science , vol.11, no.1, pp.151-156, 2022 (Peer-Reviewed Journal)
2022
20227. Biosynthesis and characterization of silver nanoparticles from Tricholoma ustale and Agaricus arvensis extracts and investigation of their antimicrobial, cytotoxic, and apoptotic potentials
KAPLAN Ö., Gökşen Tosun N., İmamoğlu R., Türkekul İ., Gökçe İ., Özgür A.
Journal of Drug Delivery Science and Technology
, vol.69, 2022 (SCI-Expanded)
2022
20228. Recombinant Production of E. coli NAD(+)-dependent DNA ligase as a Target for Antibacterial Drug Discovery
KAPLAN Ö., Imamoglu R., Gokce I.
KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE
, vol.25, no.1, pp.19-24, 2022 (ESCI)
2022
20229. Green synthesis of silver nanoparticles using Schizophyllum commune and Geopora sumneriana extracts and evaluation of their anticancer and antimicrobial activities
Goksen Tosun N., Kaplan O., TÜRKEKUL İ., GÖKÇE İ., Ozgur A.
PARTICULATE SCIENCE AND TECHNOLOGY
, vol.40, no.7, pp.801-811, 2022 (SCI-Expanded)
2022
202210. Biosynthesis of Silver Nanoparticles Using White Propolis Extract as a Reduction Agent and Optimized by Box-Behnken Design
Goksen Tosun N., Kaplan O.
KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE
, vol.25, no.5, pp.933-945, 2022 (ESCI)
2021
202111. High-Level Production of MMLV Reverse Transcriptase Enzyme in Escherichia coli
Kaplan Ö., İmamoğlu R., Gökçe İ.
International Journal of Advances in Engineering and Pure Sciences , vol.33, no.4, pp.549-555, 2021 (Peer-Reviewed Journal)
2021
202112. Development of a Fluorescent Protein Based FRET Biosensor for Determination of Protease Activity
İncir İ., Kaplan Ö., Bilgin S., Gökçe İ.
SAUJS , vol.25, no.5, pp.1235-1244, 2021 (Peer-Reviewed Journal)
2021
202113. Microwave-assisted green synthesis of silver nanoparticles using crude extracts of Boletus edulis and Coriolus versicolor: Characterization, anticancer, antimicrobial and wound healing activities
Kaplan Ö., Tosun N. G., Ozgur A., Tayhan S. E., BİLGİN S., TÜRKEKUL İ., et al.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
, vol.64, 2021 (SCI-Expanded)
2021
202114. The relationship between DIRAS1 gene and idiopathic generalized epilepsy in the Turkish population
Kaplan Ö., Pekmez M., Akinci Y., Atakli H. D., Eren F., Dirican A. C., et al.
GENE REPORTS
, vol.23, 2021 (ESCI)
2021
202115. Recombinant production and characterization of Aspergillus niger prolyl endopeptidase enzyme for gluten-free food production
Şenol Yılmaz B., Kaplan Ö., İmamoğlu R., Gökçe İ.
International Journal of Agriculture Environment and Food Sciences
, vol.5, no.3, pp.287-293, 2021 (Peer-Reviewed Journal)
2021
202116. Optimization of the green synthesis of silver nanoparticle with Box-Behnken design: Using Aloe vera plant extract as a reduction agent
Gökşen Tosun N., Kaplan Ö.
SAUJS , vol.25, no.3, pp.787-800, 2021 (Peer-Reviewed Journal)
2021
202117. Recombinant production of Thermus aquaticus single-strand binding protein for usage as PCR enhancer
Kaplan Ö., İmamoğlu R., Şahingöz İ., Gökçe İ.
International Advanced Researches and Engineering Journal , vol.5, no.1, pp.42-46, 2021 (Peer-Reviewed Journal)
2021
202118. Biosynthesis of silver nanoparticles from Teucrioside and investigation of its antibacterial activity
Kaplan Ö., Gökşen Tosun N.
Cumhuriyet Science Journal , vol.42, no.1, pp.60-67, 2021 (Peer-Reviewed Journal)
Papers Presented at Peer-Reviewed Scientific Conferences
2021
20211. Development of One-Step RT-PCR Kit for Diagnosis of COVID-19
GÖKÇE İ., ÖZGÜR A., TAYHAN Y., KAPLAN Ö., GÖKŞEN TOSUN N., İMAMOĞLU R., et al.
3rd Eurasia Biochemical Approaches & Technologies Congress (EBAT), Antalya, Turkey, 4 November - 05 December 2021, (Summary Text)
2021
20212. Green Synthesis of Silver Nanoparticles Using Armillaria Mellea and Xerocomellus Chrysenteron Extracts and Evaluation of Their Antimicrobial and Anticancer Potentials
ÖZGÜR A., GÖKŞEN TOSUN N., KAPLAN Ö., TÜRKEKUL İ., GÖKÇE İ.
3rd Eurasia Biochemical Approaches & Technologies Congress (EBAT), Antalya, Turkey, 4 - 07 November 2021, (Summary Text)
2016
20163. Expression purification and characterization of recombinant proteinase K from Tritirachium Album Limber
İmamoğlu R., KAPLAN Ö., BİLGİN S., GÖKÇE İ.
Pichia 2016, 3 - 06 April 2016, (Summary Text)
2016
20164. Expression of Thermus aquaticus single strand binding protein in Pichia pastoris for molecular biology applications
Şahingöz İ., KAPLAN Ö., BİLGİN S., ULUSU Y.
Pichia 2016, 3 - 06 April 2016
2016
20165. Production of recombinant UnaG fluorescent protein in Pichia pastoris for Improving BILIRUBIN biosensor
KAPLAN Ö., Bozkurt Y., ULUSU Y., GÖKÇE İ.
Pichia 2016, 3 - 06 April 2016
Funded Projects
2019 - 2023
2019 - 2023
Mcl-1 Protein İnhibitörü Yüklü Nanopartiküllerin Kanser Hücreleri Üzerindeki Sitotoksik ve Apoptotik Etkilerinin Araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
ARDA E. Ş. N. (Executive), PABUCCUOĞLU S. K., PEKMEZ M., KAPLAN Ö., MERTOĞLU E., GÖK M. K., et al.
2021 - 2022
2021 - 2022
Yeni Nesil Hsp90 İnhibitörlerinin (Debio-0932 ve BIIB021) İnsan Kolorektal ve Karaciğer Kanseri Hücre Hatlarında Antikanser Özelliklerinin İncelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
Özgür A.(Executive), Kaplan Ö., Gökşen Tosun N.
2021 - 2022
2021 - 2022
Investigation of Cytotoxic and Apoptotic Effects of Metallic Nanoparticles Synthesized with Lactarius Deliciosus Mushroom Extract on Breast Cancer
Project Supported by Higher Education Institutions , BAP Research Project
Özgür A.(Executive), Kaplan Ö., Türkekul İ., Gökşen Tosun N.
2019 - 2020
2019 - 2020Rekombinant İnsan Eritropoietinin E. coli Ekspresyon Sisteminde Çözünür Formda Eldesi, Saflaştırılması ve Karakterizasyonu
TUBITAK Project , 1002 - Quick Support Program
Kaplan Ö., İmamoğlu R.(Executive), Bilgin S.
2017 - 2020
2017 - 2020
Hepatit B ve Hepatit C Hastalıkları İçin Tıbbi Tanı Kiti Yapımı
Project Supported by Other Official Institutions
Kaplan Ö., İmamoğlu R., Gökçe İ.(Executive)
2015 - 2016
2015 - 2016TANI KİTLERİNİN GELİŞTİRİLMESİ İÇİN TERS TRANSKRİPTAZ ve DNA POLİMERAZ ENZİMİNİN ÜRETİLMESİ
Project Supported by Other Official Institutions
Kaplan Ö. (Executive)
2013 - 2014
2013 - 2014E.coli DNA Ligaz Enziminin Rekombinant Olarak Üretilmesi, Saflaştırılması ve Karakterizasyonu
TUBITAK Project
KAPLAN Ö. (Executive)
Patent
2025
2025Protein esaslı nanopartiküler sistemlerin sentezi
Patent
Registered / Approved, The Invention Registration Number: TR 2022 012178 B , Standard Registration
Awards
Scholarships
2016 - Present
2016 - Present2211-A Yurt İçi Doktora Burs Programı
TUBITAK
2015 - 2016
2015 - 2016