Molecular Hematology Working Group

Molecular Hematology Working Group (MOLHEM) has been conducting research activities for a long time within the Genetics Department of Istanbul University, Institute of Aziz Sancar Experimental Medicine Research. Besides Prof. Dr. Muge Sayitoglu and senior post doc researcher Dr. Yücel Erbilgin, PhD candidates and MSc students who are actively continuing their education in the genetics graduate programs are working in the group. Main research areas are rare and complex hematological diseases and primary immune deficiencies. Genome-wide analysis and functional studies on sporadic and hereditary leukemias and lymphomas, high risk leukemias (bi-phenotypic, Ph-like, T-ALL etc.), hereditary anemias, primary immunodeficiencies (severe combined, common variable, complement related etc.) are the main topics of ongoing projects.

Recent Publications

Perception and management of cancer predisposition in pediatric cancer centers: A European-wide questionnaire-based survey

Lazic J., Haas O. A., Özbek U., Ripperger T., Byrjalsen A., Te Kronnie G., et al.
Pediatric Blood and Cancer, 2023 (SCI-Expanded)

A Genetic Assessment of Dopamine Agonist-Induced Impulse Control Disorder in Patients with Prolactinoma.

Sahin S., Sudutan T., Kavla Y., Durcan E., Özogul Y. Y., Poyraz B. C., et al.
The Journal of clinical endocrinology and metabolism, 2022 (SCI-Expanded)

AXIN2 VARIATIONS MAY CONTRIBUTE TO INCREASED RISK OF PEDIATRIC T-ALL

Erbilgin Y., Tozan Küçükcankurt F., Sayitoğlu M.
Acta Medica Nicomedia, vol.5, no.3, pp.193-198, 2022 (Peer-Reviewed Journal)

Modeling Blast Crisis Using Mutagenized Chronic Myeloid Leukemia-Derived Induced Pluripotent Stem Cells (iPSCs)

Imeri J., Desterke C., Marcoux P., Telliam G., Sanekli S., Barreau S., et al.
Cells, vol.12, no.4, 2023 (SCI-Expanded)

Obstacles and expectations of rare disease patients and their families in Türkiye: ISTisNA project survey results

HATIRNAZ NG Ö., Sahin I., ERBİLGİN Y., ÖZDEMİR Ö., YÜCESAN E., Erturk N., et al.
Frontiers in Public Health, vol.10, 2023 (SCI-Expanded)

Dasatinib-related pleural effusion and lymphocytosis rates are different between adult and pediatric patients with Philadelphia chromosome-positive leukemias: Are age and comorbidities only to blame?

Kılıçaslan N. A., Börekçi Ş., Özdemir G. N., Sayitoğlu M., Eşkazan A. E.
Expert review of respiratory medicine, vol.16, pp.849-852, 2022 (SCI-Expanded)

Akut Lösemi Hücre serilerinde beta katenin siRNA uygulamaları

SAYİTOĞLU M.
Deneysel Tıp, vol.2, no.3, pp.16-22, 2012 (Peer-Reviewed Journal)

Kronik Myeloid Lösemide BCR-ABL Füzyon Transkriptinin Eş Zamanlı PCR ile Kantitasyonu İçin Referans Plazmid Oluşturulması

NG Y. Y., Yılmaz Z. H., HATIRNAZ NG Ö., SAYİTOĞLU M.
Deneysel Tıp Araştırma Enstitüsü Dergisi, vol.7, no.13, pp.93-100, 2017 (Peer-Reviewed Journal)

8q24 bölgesi çocukluk çağı lenfoblastik lösemiler için potansiyel risk oluşturur mu?

HATIRNAZ N. Ö., can i., FIRTINA S., ERBİLGİN Y., ÖZBEK U., SAYİTOĞLU M.
Deneysel Tıp Dergisi, 2018 (Peer-Reviewed Journal)

Kronik Lenfositik Losemide Genetik Ozellikler ve TP53 Mutasyonu

ERDOĞAN ÖZÜNAL I., ELVERDİ T., EŞKAZAN A. E., SALİHOĞLU A., AR M. C., ÖNGÖREN Ş., et al.
Cerrahpaşa Medical Journal, 2021 (Peer-Reviewed Journal)