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Publication
50
Open Access
2
UN Sustainable Development Goals
Announcements & Documents
Lecture Note
Moleküler Biyoloji ve Genetiğin Uygulamaları Ders Notu
Lecture Note
10/31/2017
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Education
2003 - 2009
2003 - 2009Doctorate
Istanbul University, Fen Bilimleri Enst., Moleküler Biyoloji Ve Genetik, Turkey
1999 - 2003
1999 - 2003Postgraduate
Istanbul University, Fen Bilimleri Enst., Moleküler Biyoloji Ve Genetik, Turkey
1995 - 1999
1995 - 1999Undergraduate
Hacettepe University, Fen Fakültesi, Biyoloji Bölümü, Turkey
Dissertations
2009
2009Doctorate
Mayada Ağır metal stresine bağlı olarak anlatım yapan genlerin karakterizasyonu
Istanbul University, Fen Bilimleri Enst., Moleküler Biyoloji Ve Genetik
2003
2003Postgraduate
Schizosaccharomyces pombe Lindner Str. liquefaciens(Osterwalder)'de farklı ortam koşullarının bakır metabolizması üzerine etkileri
Istanbul University, Fen Bilimleri Enst., Molekküler Biyoloji Ve Genetik
Foreign Languages
C1 Advanced
C1 AdvancedEnglish
Research Areas
Life Sciences
Molecular Biology and Genetics
Genetic Engineering
Animal Molecular Genetics
Natural Sciences
Academic Positions
2017 - Present
2017 - PresentAssistant Professor
Istanbul University, Faculty of Science, Moleküler Biyoloji ve Genetik Bölümü
2002 - Present
2002 - PresentResearch Assistant PhD
Istanbul University, Faculty of Science, Depertment of Biology
Courses
Supervised Theses
in Progress
in ProgressPostgraduate
Ko-kültür Sistemiyle Antimikrobiyal Peptid Eldesi Üzerine Çalışmalar
Tarhan Ç. (Advisor)
A.Yanık(Student)
in Progress
in ProgressPostgraduate
Schizosaccharomyces pombe'de Metformin'in Hücre Yaşlanmasına Etkisi Üzerine Çalışmalar
Tarhan Ç. (Advisor)
C.Şeylan(Student)
2020
2020Postgraduate
Schizosaccharomyces pombe'de B-Hidroksibütirat Keton Cisimciğinin Hücre Yaşlanmasına Etkisi Üzerine Çalışmalar
Tarhan Ç. (Advisor)
H.ULUDAĞ(Student)
Articles
All (12)
SCI-E, SSCI, AHCI (8)
SCI-E, SSCI, AHCI, ESCI (8)
Scopus (8)
TRDizin (2)
Other Publications (1)
2025
20251. The naa40 Deletion Is Associated with Extended Chronological Lifespan and Changes in Energy and Lipid Metabolism in Fission Yeast
Çalici Z., Özden B., Tarhan Ç.
Microbiology (Russian Federation)
, vol.94, no.5, pp.748-755, 2025 (SCI-Expanded)
2024
20242. Synbiotic supplementation ameliorates anxiety and myocardial ischaemia–reperfusion injury in hyperglycaemic rats by modulating gut microbiota
Tarhan Ç.
EXPERIMENTAL PHYSIOLOGY
, vol.28, pp.1-14, 2024 (SCI-Expanded)
2023
20233. Functional Annotation of Uncharacterised Proteins Whose Expression Patterns Affect the Lifespan under Metformin Treatment in Fission Yeast
TARHAN Ç., ÇALICI S. Z., ÖZDEN B.
European Journal of Biology
, vol.82, no.2, 2023 (Scopus)
2023
20234. Evaluation of Proteins Released to Medium in Yeast-Bacteria Co-culture System
Yanık A., Tarhan Ç.
Journal of advanced research in natural and applied sciences (Online) , vol.9, no.2, pp.488-498, 2023 (Peer-Reviewed Journal)
2023
20235. Metformin extends the chronological lifespan of fission yeast by altering energy metabolism and stress resistance capacity.
Şeylan C., Tarhan Ç.
FEMS yeast research
, vol.23, 2023 (SCI-Expanded)
2021
20216. Effects of Scilla autumnalis Extracts on U87-MG Human Glioblastoma Cells
Pekmez M., Tarhan Ç., Zeytunluoğlu A., Turan M., Mete Ş. B., Köseler A.
Kafkas Tıp Bilimleri Dergisi , vol.11, no.2, pp.299-306, 2021 (Peer-Reviewed Journal)
2021
20217. Transcriptome sequencing and screening of genes related to glucose availability in Schizosaccharomyces pombe by RNA-seq analysis
Tarhan Ç., Çakır Ö.
GENETICS AND MOLECULAR BIOLOGY
, vol.44, no.3, 2021 (SCI-Expanded)
2019
20198. A Genome-Wide Screen for Wortmannin-Resistant Mutants in Schizosaccharomyces pombe: The Phosphorylation-Impaired Mutants Are Resistant to Signaling Defect
Yilmazer M., Kartal B., Tarhan C., Ozarabaci I., Akcaalan S., Ozkan E., et al.
DNA AND CELL BIOLOGY
, vol.38, pp.1427-1436, 2019 (SCI-Expanded)
2017
20179. Palmiye yağı ve kanser gerçeği
Ertan H., Arı Ş., Günaydın K., Karagöz A., Turgut Kara N., Ay M., et al.
Herkese Bilim Teknoloji , vol.47, pp.6-7, 2017 (Non Peer-Reviewed Journal)
2012
201210. Does copper stress lead to spindle misposition-dependent cell cycle arrest?
Tarhan C., Sarikaya A. T.
GENETICS AND MOLECULAR RESEARCH
, vol.11, no.4, pp.3824-3834, 2012 (SCI-Expanded)
2010
201011. Expression of Human A4V Mutant Cu,Zn Superoxide Dismutase in Schizosaccharomyces pombe: Investigations of its Toxic Properties
Karaer S., Tarhan C., Pekmez M., HAMAD I., Arda N., Sarikaya A. T.
BIOCHEMICAL GENETICS
, vol.48, no.1-2, pp.113-124, 2010 (SCI-Expanded, Scopus)
2007
200712. The effect of superoxide dismutase deficiency on zinc toxicity in Schizosaccharomyces pombe
Tarhan C., Pekmez M., Karaer S., Arda N., Sarikaya A. T.
JOURNAL OF BASIC MICROBIOLOGY
, vol.47, no.6, pp.506-512, 2007 (SCI-Expanded, Scopus)
Papers Presented at Peer-Reviewed Scientific Conferences
2023
20231. Pioglitazone Increase Healthspan Possibly by Reducing Oxidative Stress in Fission Yeast
Çalıcı S. Z., Tarhan Ç., Özden B.
IX. International Congress of Molecular Medicine, İstanbul, Turkey, 18 - 20 December 2023, pp.16-17, (Summary Text)
2023
20232. ANALYSIS OF UPREGULATED-UNCHARACTERIZED GENES INFLUENCING LIFESPAN UNDER METFORMIN TREATMENT IN FISSION YEAST
Tarhan Ç., Çalıcı Z., Özden B.
3rd INTERNATIONAL CONGRESS ON CONTEMPORARY SCIENTIFIC RESEARCH held on August 7-8, 2023 / Adana, Türkiye, Adana, Turkey, 7 - 08 August 2023, pp.54-55, (Summary Text)
2023
20233. ANALYSIS OF UPREGULATED-UNCHARACTERIZED GENES INFLUENCING LIFESPAN UNDER METFORMIN TREATMENT IN FISSION YEAST
Tarhan Ç., Çalıcı S. Z., Özden B.
3. INTERNATIONAL CONGRESS ON CONTEMPORARY SCIENTIFIC RESEARCH, Adana, Turkey, 7 - 08 August 2023, pp.282, (Summary Text)
2022
20224. Effects of The Active Ingredient of Green Tea Epigallocatechin gallate (EGCG) Polyphenol on Cell Metabolism and Aging
Tarhan Ç., Çetin B. N.
5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022), Ankara, Turkey, 23 - 25 November 2022, pp.113, (Summary Text)
2019
20195. Puccinellia distans - A potential plant to reveal boron toxicity and salt tolerance mechanisms
Hakki E. E., Pandey A., Khan M. K., Hamurcu M., Celik O., Gezgin S., et al.
European Biotechnology Congress, Valencia, Spain, 11 - 13 April 2019, vol.305, (Summary Text)
2019
20196. A genome-wide screen for wortmann in and hydrogen peroxide resistant mutants in Schizosaccharomyces pombe
Yılmazer M., Kartal B., Tarhan Ç., Özarabacı İ., Akçaalan S., Özkan E., et al.
7th International Congress of the Molecular Biology Association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, vol.1, no.1, pp.163, (Summary Text)
2019
20197. METFORMIN INCREASES LIFESPAN BY COMPLICATED MECHANISMS IN SCHIZOSACCHAROMYCES POMBE
ŞEYLAN C., KOÇ İ., TARHAN Ç.
7th International Congress of the Molecular Biology Association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, pp.18, (Summary Text)
2019
20198. Effect of beta-hydroxybutyrate in aging process Schizosaccharomyces pombe
Uludağ H., TARHAN Ç., ÇAKIR Ö., Ataözü M.
7th international congress of The molecular Biology association of Turkey, İstanbul, Turkey, 27 - 29 September 2019, pp.81, (Full Text)
2015
20159. Evrimde Moleküler Süreçler
TARHAN Ç.
V. Evrim Bilim ve Eğitim Sempozyumu 2015, İstanbul, Turkey, 19 - 20 December 2015, pp.1-2, (Full Text)
2013
201310. Absence of the Indy protein homolog prolongs the life span in the presence of high glucose levels in Schizosaccharomyces pombe
TARHAN Ç., TOPAL SARIKAYA A., Malcı A.
Pombe 2013, 7th International Fission Yeast Meeting 24 – 29 June 2013 | London, UK, United Kingdom, 1 - 04 June 2013, pp.151, (Full Text)
2013
201311. The effects of Astragalus chrysochlorus crude extract on cancer model of Schizosaccharomyces pombe cells
Karaer Uzuner S., Tarhan Ç., Arı Ş.
Pombe 2013, 7th International Fission Yeast Meeting, London, United Kingdom, 1 - 04 June 2013, pp.188, (Full Text)
2013
201312. Hydrocortisone effect on Schizosaccharomyces pombe's rad17+ gene expression.
TARHAN Ç., ŞATIR T. M., YILMAZER M., KARAER UZUNER S.
EMBO Conference Pombe 2013 7th International Fission Yeast Meeting, Londra, United Kingdom, 1 - 04 May 2013, no.185, pp.323, (Full Text)
2011
201113. The effect of copper stress on expression of the ace2 gene in Schizosaccharomyces pombe, another piece of puzzle
Tarhan Ç., Jafari Ghods F., PALABIYIK B., Çetinkaya B., Topal Sarıkaya A.
The 6th International Fission Yeast Meeting, United States Of America, 1 - 04 June 2011, vol.1, pp.225, (Full Text)
2010
201014. Does Copper Stress Affect the Organization of Microtubule in the Fission Yeast
TARHAN Ç., Topal SARIKAYA A.
Power of Microbes in Industry and Environment, Central European Symposium on Industrial Microbiology and Microbial Ecology, Croatia, 1 - 04 October 2010, pp.1-2, (Full Text)
2009
200915. Gene Expression Profiling of Copper Induced Responces in the Fission Yeast
TARHAN Ç., Topal SARIKAYA A.
The Fifth International Fission Yeast Meeting, Pombe 2009, Japan, 1 - 04 October 2009, pp.320, (Full Text)
2008
200816. Schizosaccharomyces pombe’de Bakır Stresine Bağlı Olarak Anlatım Yapan Genlerin Farklılık Gösterim Yöntemiyle Araştırılması
TARHAN Ç., Topal SARIKAYA A.
Ulusal Maya Moleküler Biyolojisi ve Biyoteknolojisi Sempozyumu, Bursa, Turkey, 1 - 04 May 2008, pp.12, (Full Text)
2007
200717. Fission yeast as a model for ALS disease
Karaer S., Tarhan C., Hamad I., Pekmez M., Arda N., Sarikaya A. T.
13th European Congress on Biotechnology (ECB 13), Barcelona, Spain, 16 - 19 September 2007, vol.131, (Summary Text)
2005
200518. Studying on Zinc Toxicty and Antioxidant Defense Mechanism in Schizosaccharomyces pombe
TARHAN Ç., PEKMEZ M., Topal SARIKAYA A.
The XXIInd International Conference on Yeast Genetics and Molecular Biiology, Slovakia, 1 - 04 September 2005, pp.36, (Full Text)
2005
200519. The cloning and expression of human ALS mutant Cu,Zn SOD into Schizosaccharomyces pombe
Karaer Uzuner S., TARHAN Ç., Topal SARIKAYA A.
The XXIInd International Conference on Yeast Genetics and Molecular Biiology, Slovakia, 1 - 04 September 2005, pp.236, (Full Text)
2005
200520. Çinko Toksisitesi ve Antioksidan Savunma Mekaniizmaları Üzerine Çlaışmalar
TARHAN Ç., PEKMEZ M., Topal SARIKAYA A.
XIV. Ulusal Biyoteknoloji Kongresi, Eskişehir, Turkey, 1 - 04 September 2005, pp.322, (Full Text)
2003
200321. Mayada farklı ortam koşullarının süperoksit dismutaz aktivitesi üzerine etkileri.
TARHAN Ç., Topal SARIKAYA A.
XIII. Biyoteknoloji Kongresi, Çanakkale, Turkey, 1 - 04 August 2003, pp.294, (Full Text)
2003
200322. The Schizosaccharomyces pombe LYS7 gene is involved in copper metabolism.
Sarikaya A., TARHAN Ç.
21st International Conference on Yeast Genetics and Molecular Biology, Gothenburg, Sweden, 7 - 12 July 2003, vol.20, (Summary Text)
2002
200223. Mayada hücre üremesi ve süperoksit dismutaz aktivitesi üzerine bakırın etkileri.
TARHAN Ç., Topal SARIKAYA A.
XVI. Ulusal Biyoloji Kongresi, Malatya, Turkey, 1 - 04 September 2002, pp.48, (Full Text)
2001
200124. Mayada ağır metal duyarlılığı üzerine pH’nın etkileri
AKMAN G., KIĞ C., TARHAN Ç., YAVUZ İ., Topal SARIKAYA A.
XII. Biyoteknoloji Kongresi, Balıkesir, Turkey, 1 - 04 September 2001, pp.132, (Full Text)
Books
2023
20232. Yaşlanmanın Moleküler Temelleri
Tarhan Ç.
in: Geleceğin Yeni Sahipleri Yaşlılar, Ahmet AKGÜL Nur Elçin BOYACIOĞLU Sera YİĞİTER, Editor, İÜC Yayınevi, İstanbul, pp.13-20, 2023
2020
20204. Virüslerin İnsan Evrimindeki Rolü
Tarhan Ç.
in: Pandemi ve Covid - 19, Selim Badur,Şadi Yenen, Editor, Ayrıntı Yayınları, İstanbul, pp.302-310, 2020
2016
20167. Evrimsel Yeniliklerin Moleküler Temelleri
TARHAN Ç.
in: Evrimin Işığında, Altınışık N.E. ve Akış I., Editor, Yazılama, İstanbul, pp.58-70, 2016
2016
20168. Epigenetics and Applications in Plants
TARHAN Ç., TURGUT KARA N.
in: Plant Omics: Trends and Applications, Hakeem, Khalid Rehman, Tombuloglu, Huseyin, Tombuloğlu, Güzin, Editor, Springer International Publishing, Zürich, pp.255-270, 2016
2013
201311. Hayvanlar Ne İster (Hayvan Bilinci, Hayvan Refahı ve İnsanın Esenliği)
TARHAN Ç.
Alfa, İstanbul, 2013
2012
201214. Derin Homoloji ve Evrimsel Yeniliklerin Ortaya Çıkışındaki Rolü
TARHAN Ç.
in: Evrim Sürüyor, Durmuş Z.Ö. ve Akış I., Editor, Yazılama, İstanbul, pp.103-113, 2012
Funded Projects
2022 - 2025
2022 - 2025Antidiyabetik ilaç metforminin Clr6 histondeasetilaz aracılı genetik düzenleme mekanizmalarının araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
Çalıcı S. Z., Tarhan Ç. (Executive)
2022 - 2024
2022 - 2024NAA40 MUTASYONUNUN Schizosaccharomyces pombede HÜCRE YAŞLANMA MEKANİZMALARI ÜZERİNE ETKİLERİNİN İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Other
TARHAN Ç. (Executive), ÇALICI S. Z., ÖZDEN B.
2022 - 2024
2022 - 2024NAA40 MUTASYONUNUN Schizosaccharomyces pombede HÜCRE YAŞLANMA MEKANİZMALARI ÜZERİNE ETKİLERİNİN İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Research Project
Çalici S. Z., Özden B., Tarhan Ç. (Executive)
2022 - 2023
2022 - 2023Antidiyabetik İlaç Metforminin Schizosaccharomyces pombe'de Gen Anlatım Profili Üzerine Etkisi
Project Supported by Higher Education Institutions , BAP MSc
TARHAN Ç. (Executive), MIRAJ H.
2020 - 2022
2020 - 2022Ko-kültür Sistemiyle Antimikrobiyal Peptid Eldesi Üzerine Çalışmalar
Project Supported by Higher Education Institutions , BAP MSc
TARHAN Ç. (Executive), YANIK A.
2020 - 2021
2020 - 2021Schizosaccharomyces pombe'de B-Hidroksibütirat Keton Cisimciğinin Hücre Yaşlanmasına Etkisi Üzerine Çalışmalar
Project Supported by Higher Education Institutions , BAP MSc
TARHAN Ç. (Executive), ULUDAĞ H.
2020 - 2021
2020 - 2021Schizosaccharomyces pombe'de Metformin'in Hücre Yaşlanmasına Etkisi Üzerine Çalışmalar
Project Supported by Higher Education Institutions , BAP MSc
TARHAN Ç. (Executive), ŞEYLAN C.
2016 - 2017
2016 - 2017Epigenetics and Applications in Plants
Project Supported by Higher Education Institutions , BAP Other
TURGUT KARA N. (Executive), TARHAN Ç.
2016 - 2017
2016 - 2017GIDALARDA TATLANDIRICI OLARAK KULLANILAN FRUKTOZ ŞURUBUNUN HÜCRE YAŞLANMASI ÜZERİNE ETKİLERİ
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive), ÇOBAN F., TARHAN Ç., ÖZDEMİR E.
2015 - 2017
2015 - 2017
İnsan hastalıklarının moleküler mekanizmalarının araştırılmasında Schizosaccharomyces pombe'nin model organizma olarak kullanılmasının optimizasyonu
Project Supported by Higher Education Institutions , BAP Research Project
PALABIYIK B. (Executive), YILMAZER M., TARHAN Ç., KARAER UZUNER S., ARICAN E., ÖZCAN F. G., et al.
2016 - 2016
2016 - 2016Schizosaccharomyces pombe'de Branched Chain Amico Acid Aminotransferase (Eca39) Geninin Yaşlanma Üzerindeki Etkisinin Araştırılması
Project Supported by Higher Education Institutions , BAP Other
KARAER UZUNER S. (Executive), ISENI T., YANIK A., TARHAN Ç.
2013 - 2016
2013 - 2016MOLEKÜLER BİYOTEKNOLOJİ LABORATUVARININ KURULMASI
Project Supported by Higher Education Institutions , BAP Guided
ARDA E. Ş. N. (Executive), UÇARLI C., ARICAN E., ALBAYRAK G., GÜREL A. F., ARI Ş., et al.
2013 - 2015
2013 - 2015Ağır Metal Stresinin Hücre Çevrimine Etkisi Üzerine Çalışmalar
Project Supported by Higher Education Institutions , BAP Other
TARHAN Ç. (Executive)
2012 - 2014
2012 - 2014Schizosaccharomyces pombe'de hücresel yaşlanma üzerine çalışmalar
Project Supported by Higher Education Institutions , BAP Research Project
TARHAN Ç. (Executive)
2013 - 2013
2013 - 2013indy geni homoloğu bakımından mutant Schizosaccharomyces pombe hücrelerinde yaşlanma üzerine çalışmalar
Project Supported by Higher Education Institutions , BAP Other
TARHAN Ç. (Executive)
2009 - 2013
2009 - 2013Mayada Superoksit dismutaz enzimine özgü çinko taşıyıcı proteinlerin araştırılması
Project Supported by Higher Education Institutions , BAP Research Project
TARHAN Ç. (Executive)
Memberships and Roles in Scientific Organizations
2008 - Present
2008 - PresentTürk Mikrobiyoloji Derneği
Member
Congress and Symposium Activities
01 July 2009 - 01 July 2009
01 July 2009 - 01 July 2009Suna Kıraç Conferences on Neurodegeneration İstanbul Stem Cells, RNAi and Neurodegeneration
Attendee
İstanbul-Turkey
01 April 2008 - 01 April 2008
01 April 2008 - 01 April 2008New Frontiers in Understanding and Treating ALS
Attendee
İstanbul-Turkey
01 May 2004 - 01 May 2004
01 May 2004 - 01 May 2004I. Ulusal Klinik ve Pratikte Kök Hücre ve Gen Tedavisi Kongresi
Attendee
İstanbul-Turkey
Citations
Total Citations (WOS): 16
h-index (WOS): 2
Jury Memberships
July-2020
July 2020Doctoral Examination
Jüri - Bezmiâlem Vakıf Üniversitesi
September-2019
September 2019Committee Of Expert
Panelist - Istanbul University
May-2019
May 2019Doctoral Examination
Jüri - İstanbul Üniversitesi
January-2019
January 2019Post Graduate
Jüri - Hacettepe Üniversitesi
March-2018
March 2018